C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: serine peptidase inhibitor, Kazal type 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000359874 SPINK5-003 ENSG00000133710 9606 + 5:148063972-148137289 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryPlacentaTestisENST00000359874
Transcript ID Ovary Placenta Testis
ENST00000359874 4.410±4.36 0.101±0.05 0.150±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000257 CIL_000257_0001 CGP 5:147880726-148137289
CIL_0001KU CIL_0001KU_0001 CGP 5:148025683-148175398

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004867 IDA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005576 NAS extracellular region
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005829 IDA cytosol
GO:0005938 IDA cell cortex
GO:0009913 IDA epidermal cell differentiation
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0016525 TAS negative regulation of angiogenesis
GO:0030155 IEA regulation of cell adhesion
GO:0030198 TAS extracellular matrix organization
GO:0030414 IEA peptidase inhibitor activity
GO:0030855 TAS epithelial cell differentiation
GO:0035315 TAS hair cell differentiation
GO:0042640 TAS anagen
GO:0045580 TAS regulation of T cell differentiation
GO:0045861 IEA negative regulation of proteolysis
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050777 TAS negative regulation of immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0097209 IDA epidermal lamellar body
GO:1902572 IEA negative regulation of serine-type peptidase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000069245 Spink5-001 protein_coding Mus_musculus 0.000000002 69

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