C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin beta 1 binding protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000360635 ITGB1BP1-005 ENSG00000119185 9606 - 2:9403475-9423229 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360635
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360635 4.340±0.00 5.005±0.00 3.309±2.28 4.968±3.40 0.661±0.00 6.096±0.00 1.351±0.82 2.774±0.06 0.266±0.00 2.988±0.88 2.805±0.71 10.849±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007AP CIL_0007AP_0002 CGP 2:8852690-9405683
CIL_0007AV CIL_0007AV_0002 CGP 2:9206765-9423547
CIL_00057K CIL_00057K_0001 CGP 2:9403475-9473101

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0002043 IDA blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:0005092 IDA GDP-dissociation inhibitor activity
GO:0005178 IPI integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005856 ISS cytoskeleton
GO:0005886 ISS plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006469 IDA negative regulation of protein kinase activity
GO:0006933 ISS negative regulation of cell adhesion involved in substrate-bound cell migration
GO:0007160 IDA cell-matrix adhesion
GO:0007219 IEA Notch signaling pathway
GO:0007229 IDA integrin-mediated signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0008565 IDA protein transporter activity
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0010764 ISS negative regulation of fibroblast migration
GO:0015031 IDA protein transport
GO:0016020 NAS membrane
GO:0016477 TAS cell migration
GO:0019900 IEA kinase binding
GO:0019901 IEA protein kinase binding
GO:0030027 IDA lamellipodium
GO:0030154 IEA cell differentiation
GO:0031214 IEA biomineral tissue development
GO:0032091 IDA negative regulation of protein binding
GO:0032148 IDA activation of protein kinase B activity
GO:0032403 IDA protein complex binding
GO:0033622 ISS integrin activation
GO:0033628 ISS regulation of cell adhesion mediated by integrin
GO:0035148 IDA tube formation
GO:0035556 TAS intracellular signal transduction
GO:0035924 IDA cellular response to vascular endothelial growth factor stimulus
GO:0043088 IDA regulation of Cdc42 GTPase activity
GO:0043113 ISS receptor clustering
GO:0044344 IDA cellular response to fibroblast growth factor stimulus
GO:0045747 IDA positive regulation of Notch signaling pathway
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050880 IDA regulation of blood vessel size
GO:0051451 ISS myoblast migration
GO:0051496 ISS positive regulation of stress fiber assembly
GO:0051781 IEA positive regulation of cell division
GO:0051894 IEA positive regulation of focal adhesion assembly
GO:0051895 IDA negative regulation of focal adhesion assembly
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0070062 IDA extracellular vesicular exosome
GO:0070373 IDA negative regulation of ERK1 and ERK2 cascade
GO:0071944 IDA cell periphery
GO:0090051 IDA negative regulation of cell migration involved in sprouting angiogenesis
GO:0090314 ISS positive regulation of protein targeting to membrane
GO:0090315 IDA negative regulation of protein targeting to membrane
GO:1900025 IDA negative regulation of substrate adhesion-dependent cell spreading
GO:2001044 ISS regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000173729 Itgb1bp1-004 protein_coding Mus_musculus 0 617
ENSMUST00000076260 Itgb1bp1-001 protein_coding Mus_musculus 0 617
ENSMUST00000172834 Itgb1bp1-006 protein_coding Mus_musculus 0 551
ENSMUST00000090834 Asap2-002 protein_coding Mus_musculus 0 436
ENSMUST00000101562 Asap2-004 protein_coding Mus_musculus 0 436
ENSMUST00000064595 Asap2-001 protein_coding Mus_musculus 0 436

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