C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sterol O-acyltransferase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000367619 SOAT1-001 ENSG00000057252 9606 + 1:179293802-179358680 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367619
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367619 5.512±0.00 3.494±0.00 1.683±0.00 1.152±0.17 3.206±0.84 1.943±0.67 0.938±0.61 2.237±1.18 2.793±1.38 5.192±0.61 0.767±0.55 4.572±0.27 5.371±1.60 3.698±1.40

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000062 IDA fatty-acyl-CoA binding
GO:0004772 IMP sterol O-acyltransferase activity
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0008203 IDA cholesterol metabolic process
GO:0010742 IMP macrophage derived foam cell differentiation
GO:0010878 IMP cholesterol storage
GO:0015485 IDA cholesterol binding
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0033344 IMP cholesterol efflux
GO:0034379 IMP very-low-density lipoprotein particle assembly
GO:0034435 IDA cholesterol esterification
GO:0034736 IDA cholesterol O-acyltransferase activity
GO:0042632 TAS cholesterol homeostasis
GO:0042986 IMP positive regulation of amyloid precursor protein biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000051396 Soat1-003 protein_coding Mus_musculus 0 1580
ENSMUST00000189661 Soat1-001 protein_coding Mus_musculus 0 1580
ENSMUST00000187987 Soat1-007 retained_intron Mus_musculus 0 342
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.00001 58
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.00003 57

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