C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: TTK protein kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000369798 TTK-001 ENSG00000112742 9606 + 6:80004605-80042527 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyOvaryPlacentaTestisENST00000369798
Transcript ID Bladder Brain Breast Colon Heart Kidney Ovary Placenta Testis
ENST00000369798 0.040±0.00 0.018±0.00 0.836±0.00 1.107±0.00 0.032±0.00 0.149±0.00 2.275±1.89 0.812±0.46 18.638±3.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006G9 CIL_0006G9_0001 CGP 6:79914812-80042527
CIL_0006G6 CIL_0006G6_0001 CGP 6:80003887-80346270

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005819 TAS spindle
GO:0006468 IEA protein phosphorylation
GO:0007051 TAS spindle organization
GO:0007052 TAS mitotic spindle organization
GO:0007093 IEA mitotic cell cycle checkpoint
GO:0007094 TAS mitotic spindle assembly checkpoint
GO:0008284 TAS positive regulation of cell proliferation
GO:0010862 TAS positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016020 IDA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0051304 IEA chromosome separation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000070326 Ttk-001 protein_coding Mus_musculus 0 1279
ENSMUST00000188445 Ttk-002 retained_intron Mus_musculus 0 1203
ENSMUST00000185913 Ttk-004 protein_coding Mus_musculus 0 819

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