C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, cAMP-dependent, catalytic, beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000370685 PRKACB-004 ENSG00000142875 9606 + 1:84144271-84238498 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaENST00000370685
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENST00000370685 0.799±0.00 0.953±0.00 1.782±0.00 4.425±2.88 11.421±0.00 0.575±0.00 1.660±0.80 5.351±0.00 5.103±4.29 0.995±0.70 0.728±0.10

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0001843 IEA neural tube closure
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004691 IDA cAMP-dependent protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005952 TAS cAMP-dependent protein kinase complex
GO:0005975 TAS carbohydrate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006094 TAS gluconeogenesis
GO:0006112 TAS energy reserve metabolic process
GO:0006468 IDA:IEA protein phosphorylation
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007188 TAS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019433 TAS triglyceride catabolic process
GO:0031625 IDA ubiquitin protein ligase binding
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 TAS intracellular signal transduction
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050796 TAS regulation of insulin secretion
GO:0051447 IEA negative regulation of meiotic cell cycle
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0070613 IEA regulation of protein processing
GO:0071377 TAS cellular response to glucagon stimulus
GO:0097338 IEA response to clozapine
GO:0097546 IEA ciliary base
GO:1901621 IEA negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005164 Prkacb-002 protein_coding Mus_musculus 0 1533
ENSMUST00000106137 Prkacb-004 protein_coding Mus_musculus 0 1389
ENSMUST00000106138 Prkacb-003 protein_coding Mus_musculus 0 1389
ENSMUST00000102515 Prkacb-001 protein_coding Mus_musculus 0 1389
ENSDART00000082143 prkacbb-001 protein_coding Danio_rerio 0 725
ENSDART00000123112 prkacbb-201 protein_coding Danio_rerio 0 719
ENSDART00000155081 prkacbb-001 protein_coding Danio_rerio 0 520

Loading