C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MPL proto-oncogene, thrombopoietin receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000372470 MPL-001 ENSG00000117400 9606 + 1:43337807-43352772 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLungOvaryPlacentaTestisENST00000372470
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Lung Ovary Placenta Testis
ENST00000372470 0.134±0.00 0.182±0.00 0.474±0.00 0.181±0.00 0.134±0.00 0.051±0.00 0.156±0.00 0.175±0.00 0.094±0.02 0.404±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008N2 CIL_0008N2_0001 VISTA 1:42758169-43359178

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004888 TAS transmembrane signaling receptor activity
GO:0004896 IEA cytokine receptor activity
GO:0005515 IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0008283 TAS cell proliferation
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0030168 TAS platelet activation
GO:0032642 IEA regulation of chemokine production
GO:0048872 IEA homeostasis of number of cells

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168404 Mpl-201 protein_coding Mus_musculus 0 1989
ENSMUST00000102671 Mpl-001 protein_coding Mus_musculus 0 1934
ENSMUST00000006556 Mpl-003 protein_coding Mus_musculus 0 1930
ENSMUST00000106375 Mpl-002 protein_coding Mus_musculus 0 1303

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