C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: triggering receptor expressed on myeloid cells 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000373122 TREM2-003 ENSG00000095970 9606 - 6:41158506-41163103 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonHeartOvaryTestisENST00000373122
Transcript ID Brain Colon Heart Ovary Testis
ENST00000373122 2.502±0.00 1.018±0.00 0.311±0.10 1.295±0.00 0.199±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008F3 CIL_0008F3_0001 VISTA 6:41112821-41713777

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002588 IDA positive regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0004872 TAS receptor activity
GO:0005576 IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0006959 TAS humoral immune response
GO:0007411 TAS axon guidance
GO:0016021 IDA integral component of membrane
GO:0045087 TAS innate immune response
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050850 IDA positive regulation of calcium-mediated signaling
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0097028 IDA dendritic cell differentiation
GO:0097110 IPI scaffold protein binding
GO:1903078 IDA positive regulation of protein localization to plasma membrane
GO:1903082 IDA positive regulation of C-C chemokine receptor CCR7 signaling pathway
GO:2000350 IDA positive regulation of CD40 signaling pathway

Homologs

No Homologs available.

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