C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000373809 CDK1-008 ENSG00000170312 9606 + 10:60780153-60794852 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000373809
Transcript ID Breast Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000373809 0.249±0.00 0.367±0.00 0.589±0.00 0.071±0.00 0.122±0.00 23.952±0.00 2.824±0.00 4.977±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GY CIL_0000GY_0002 CGP 10:60026298-60794852

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000083 TAS regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000165 TAS MAPK cascade
GO:0000186 TAS activation of MAPKK activity
GO:0000187 TAS activation of MAPK activity
GO:0000226 TAS microtubule cytoskeleton organization
GO:0000278 TAS mitotic cell cycle
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 NAS:IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004693 IDA cyclin-dependent protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005876 IDA spindle microtubule
GO:0006260 TAS DNA replication
GO:0006281 TAS DNA repair
GO:0006468 IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007067 IEA mitotic nuclear division
GO:0007077 TAS mitotic nuclear envelope disassembly
GO:0007098 TAS centrosome cycle
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0007344 TAS pronuclear fusion
GO:0007411 TAS axon guidance
GO:0008286 TAS insulin receptor signaling pathway
GO:0008353 IDA RNA polymerase II carboxy-terminal domain kinase activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0014038 TAS regulation of Schwann cell differentiation
GO:0016020 IDA membrane
GO:0016477 TAS cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0030496 IDA midbody
GO:0030855 IEP epithelial cell differentiation
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0034501 IDA protein localization to kinetochore
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043066 IDA negative regulation of apoptotic process
GO:0045087 TAS innate immune response
GO:0045995 TAS regulation of embryonic development
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051403 TAS stress-activated MAPK cascade
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070062 IDA extracellular vesicular exosome
GO:0072686 IDA mitotic spindle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020099 Cdk1-001 protein_coding Mus_musculus 0 440
ENSMUST00000119827 Cdk1-002 protein_coding Mus_musculus 0 427

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