C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: chloride intracellular channel 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374379 CLIC4-001 ENSG00000169504 9606 + 1:24745357-24844324 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374379
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374379 78.653±0.00 41.563±0.00 32.461±0.00 32.926±15.39 51.787±7.56 69.311±44.17 58.908±23.14 37.371±21.16 50.381±42.93 90.240±52.57 8.437±4.77 24.903±9.74 47.689±7.55 37.238±21.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZX CIL_0007ZX_0001 VISTA 1:24547215-25148615
CIL_0002GR CIL_0002GR_0002 CGP 1:24631716-24844324

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001886 IEA endothelial cell morphogenesis
GO:0005247 IEA voltage-gated chloride channel activity
GO:0005254 TAS chloride channel activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005813 IDA centrosome
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0005902 IDA microvillus
GO:0005911 IDA cell-cell junction
GO:0006821 NAS chloride transport
GO:0007035 IEA vacuolar acidification
GO:0009566 IEA fertilization
GO:0009986 IDA cell surface
GO:0015629 TAS actin cytoskeleton
GO:0015630 IDA microtubule cytoskeleton
GO:0016363 IDA nuclear matrix
GO:0030154 TAS cell differentiation
GO:0030216 IMP keratinocyte differentiation
GO:0030336 IDA negative regulation of cell migration
GO:0030496 IDA midbody
GO:0031410 IEA cytoplasmic vesicle
GO:0034707 IEA chloride channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035088 NAS establishment or maintenance of apical/basal cell polarity
GO:0035264 IEA multicellular organism growth
GO:0044070 IEA regulation of anion transport
GO:0045177 IDA apical part of cell
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0051493 NAS regulation of cytoskeleton organization
GO:0061299 IEA retina vasculature morphogenesis in camera-type eye
GO:0070062 IDA extracellular vesicular exosome
GO:0071277 IMP cellular response to calcium ion
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000037099 Clic4-001 protein_coding Mus_musculus 0 1085
ENSMUST00000143370 Clic4-002 retained_intron Mus_musculus 0 484
ENSDART00000035944 clic5a-001 protein_coding Danio_rerio 0 220

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