C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proprotein convertase subtilisin/kexin type 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000376752 PCSK5-001 ENSG00000099139 9606 + 9:75890705-76195889 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376752
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376752 9.877±0.00 3.351±0.00 0.334±0.00 0.716±0.07 3.022±1.67 3.208±1.24 0.738±0.22 0.291±0.13 0.795±0.54 1.658±1.20 0.192±0.12 2.985±1.66 4.437±0.96 1.595±1.02

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0002001 IEP renin secretion into blood stream
GO:0004252 IDA:IEA serine-type endopeptidase activity
GO:0005615 IBA extracellular space
GO:0005794 ISS Golgi apparatus
GO:0005796 TAS Golgi lumen
GO:0006465 IDA signal peptide processing
GO:0006508 IEA proteolysis
GO:0007267 TAS cell-cell signaling
GO:0007507 ISS heart development
GO:0007566 ISS embryo implantation
GO:0008233 IDA:IEA peptidase activity
GO:0009952 IMP anterior/posterior pattern specification
GO:0016021 IEA integral component of membrane
GO:0016485 IDA protein processing
GO:0016486 IDA peptide hormone processing
GO:0019058 IEP viral life cycle
GO:0030141 ISS secretory granule
GO:0030323 ISS respiratory tube development
GO:0032455 TAS nerve growth factor processing
GO:0035108 ISS limb morphogenesis
GO:0042089 ISS cytokine biosynthetic process
GO:0042277 ISS peptide binding
GO:0043043 IDA peptide biosynthetic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048566 IMP embryonic digestive tract development
GO:0048706 IMP embryonic skeletal system development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000050715 Pcsk5-202 protein_coding Mus_musculus 0 3853
ENSMUST00000025618 Pcsk5-201 protein_coding Mus_musculus 0 3290
ENSMUST00000098391 Pcsk6-002 protein_coding Mus_musculus 0 462
ENSMUST00000055576 Pcsk6-001 protein_coding Mus_musculus 0 462
ENSMUST00000176209 Pcsk6-003 protein_coding Mus_musculus 0 420
ENSMUST00000177369 Pcsk6-005 retained_intron Mus_musculus 0 252

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