C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAS guanyl releasing protein 2 (calcium and DAG-regulated)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000377494 RASGRP2-007 ENSG00000068831 9606 - 11:64726911-64743789 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastMuscleTestisENST00000377494
Transcript ID Adipose Brain Breast Muscle Testis
ENST00000377494 1.542±0.00 1.064±0.00 0.922±0.00 0.139±0.00 1.616±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005J6 CIL_0005J6_0002 CGP 11:64606174-64745456
CIL_0005J1 CIL_0005J1_0002 CGP 11:64726911-64760297

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001558 NAS regulation of cell growth
GO:0005085 IEA:IDA guanyl-nucleotide exchange factor activity
GO:0005509 NAS:IEA calcium ion binding
GO:0005622 IEA intracellular
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0007165 TAS signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007265 NAS Ras protein signal transduction
GO:0007596 TAS blood coagulation
GO:0008289 TAS lipid binding
GO:0019992 NAS diacylglycerol binding
GO:0030054 IEA cell junction
GO:0030168 TAS platelet activation
GO:0032854 IDA positive regulation of Rap GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0043005 IEA neuron projection
GO:0043547 IEA positive regulation of GTPase activity
GO:0045202 IEA synapse
GO:0051056 IEA regulation of small GTPase mediated signal transduction
GO:0071277 IDA cellular response to calcium ion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000035716 Rasgrp2-001 protein_coding Mus_musculus 0 2471
ENSMUST00000167240 Rasgrp2-201 protein_coding Mus_musculus 0 2466
ENSMUST00000113476 Rasgrp2-021 protein_coding Mus_musculus 0 2466
ENSMUST00000127021 Rasgrp2-024 nonsense_mediated_decay Mus_musculus 0 2248
ENSMUST00000135532 Rasgrp2-003 retained_intron Mus_musculus 0 992
ENSMUST00000149205 Rasgrp2-004 processed_transcript Mus_musculus 0 961
ENSMUST00000113472 Rasgrp2-002 protein_coding Mus_musculus 0 928
ENSMUST00000148906 Rasgrp2-015 retained_intron Mus_musculus 0 396
ENSMUST00000152022 Rasgrp2-016 retained_intron Mus_musculus 0 353

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