C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cubilin (intrinsic factor-cobalamin receptor)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000377833 CUBN-001 ENSG00000107611 9606 - 10:16823964-17129831 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377833
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377833 0.243±0.00 0.231±0.00 0.056±0.02 0.247±0.00 0.156±0.00 0.036±0.01 2.229±2.14 0.127±0.13 0.116±0.00 0.105±0.08 0.370±0.21 0.685±0.38 0.890±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00063X CIL_00063X_0002 CGP 10:16590611-17129831
CIL_0000IU CIL_0000IU_0002 CGP 10:16823964-17202054

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001894 NAS tissue homeostasis
GO:0004872 IEA receptor activity
GO:0005215 TAS transporter activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005903 IEA brush border
GO:0005905 IEA coated pit
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0006898 NAS receptor-mediated endocytosis
GO:0008202 TAS steroid metabolic process
GO:0008203 IEA cholesterol metabolic process
GO:0009235 TAS cobalamin metabolic process
GO:0010008 TAS endosome membrane
GO:0015889 TAS cobalamin transport
GO:0016020 TAS membrane
GO:0016324 IDA apical plasma membrane
GO:0030139 IDA endocytic vesicle
GO:0031232 NAS extrinsic component of external side of plasma membrane
GO:0031419 IEA cobalamin binding
GO:0031526 NAS brush border membrane
GO:0042157 TAS lipoprotein metabolic process
GO:0042359 TAS vitamin D metabolic process
GO:0042803 IDA protein homodimerization activity
GO:0042953 IEA lipoprotein transport
GO:0043202 TAS lysosomal lumen
GO:0044281 TAS small molecule metabolic process
GO:0045177 IEA apical part of cell
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000091436 Cubn-001 protein_coding Mus_musculus 0 6316

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