C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SKI proto-oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000378536 SKI-001 ENSG00000157933 9606 + 1:2228695-2310119 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378536
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378536 5.637±0.00 19.491±0.00 3.139±0.00 12.617±0.00 31.406±0.00 11.743±7.70 6.112±4.82 6.876±3.53 3.633±0.00 13.195±9.34 6.708±4.01 19.872±13.98 11.052±2.42 15.563±9.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QV CIL_0007QV_0001 VISTA 1:1910870-2513425

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001843 ISS neural tube closure
GO:0002089 ISS lens morphogenesis in camera-type eye
GO:0003682 IEA chromatin binding
GO:0003714 IMP transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 ISS transcription factor complex
GO:0005737 ISS cytoplasm
GO:0005813 IDA centrosome
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007179 NAS transforming growth factor beta receptor signaling pathway
GO:0008270 IDA zinc ion binding
GO:0008283 NAS cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0009948 ISS anterior/posterior axis specification
GO:0010467 TAS gene expression
GO:0010626 IGI negative regulation of Schwann cell proliferation
GO:0014902 IDA myotube differentiation
GO:0016604 IDA nuclear body
GO:0016605 IDA PML body
GO:0017053 ISS transcriptional repressor complex
GO:0019901 IPI protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0021772 ISS olfactory bulb development
GO:0022011 ISS myelination in peripheral nervous system
GO:0030177 NAS positive regulation of Wnt signaling pathway
GO:0030326 ISS embryonic limb morphogenesis
GO:0030509 TAS BMP signaling pathway
GO:0030512 IGI negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0031064 IEA negative regulation of histone deacetylation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032926 IDA negative regulation of activin receptor signaling pathway
GO:0035019 ISS somatic stem cell maintenance
GO:0042981 IBA regulation of apoptotic process
GO:0043010 ISS camera-type eye development
GO:0043234 IDA protein complex
GO:0043388 IDA positive regulation of DNA binding
GO:0043585 ISS nose morphogenesis
GO:0045668 IDA negative regulation of osteoblast differentiation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IPI:IEA SMAD binding
GO:0046811 ISS histone deacetylase inhibitor activity
GO:0048147 ISS negative regulation of fibroblast proliferation
GO:0048593 ISS camera-type eye morphogenesis
GO:0048741 ISS skeletal muscle fiber development
GO:0048870 NAS cell motility
GO:0060021 ISS palate development
GO:0060041 ISS retina development in camera-type eye
GO:0060325 ISS face morphogenesis
GO:0060349 ISS bone morphogenesis
GO:0060395 IDA SMAD protein signal transduction
GO:0070207 IDA protein homotrimerization
GO:0070491 IPI repressing transcription factor binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000030917 Ski-001 protein_coding Mus_musculus 0 3282
ENSMUST00000084103 Ski-003 protein_coding Mus_musculus 0 2702
ENSMUST00000129314 Ski-002 processed_transcript Mus_musculus 0 1709

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