C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000378688 HTR2A-001 ENSG00000102468 9606 - 13:46831550-46896038 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyMuscleOvaryTestisENST00000378688
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Muscle Ovary Testis
ENST00000378688 0.005±0.00 0.059±0.00 0.025±0.00 0.889±0.00 0.194±0.06 0.011±0.00 0.180±0.00 0.177±0.00 0.060±0.03 0.190±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00021K CIL_00021K_0002 CGP 13:46771256-46897076

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004993 IDA serotonin receptor activity
GO:0005886 IDA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006874 IDA cellular calcium ion homeostasis
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007202 IDA activation of phospholipase C activity
GO:0007210 IMP serotonin receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008144 IDA drug binding
GO:0010513 IDA positive regulation of phosphatidylinositol biosynthetic process
GO:0014065 IDA phosphatidylinositol 3-kinase signaling
GO:0016021 IEA integral component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0042493 IDA response to drug
GO:0046883 IEA regulation of hormone secretion
GO:0050795 IEA regulation of behavior
GO:0051209 IDA release of sequestered calcium ion into cytosol
GO:0051378 IDA serotonin binding
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0071886 IDA 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000036653 Htr2a-201 protein_coding Mus_musculus 0 1690

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