C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pyruvate dehydrogenase kinase, isozyme 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000379162 PDK3-001 ENSG00000067992 9606 + X:24465221-24534425 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonKidneyLiverLungMusclePlacentaENST00000379162
Transcript ID Adrenal Colon Kidney Liver Lung Muscle Placenta
ENST00000379162 0.908±0.00 1.085±0.23 0.914±0.05 0.830±0.40 1.011±0.32 0.068±0.00 0.437±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084H CIL_00084H_0001 VISTA X:24441239-25041771

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004740 IDA pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005739 TAS mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006006 IEA glucose metabolic process
GO:0006090 TAS pyruvate metabolic process
GO:0008219 IEA cell death
GO:0010510 IMP regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010906 IMP regulation of glucose metabolic process
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0035357 IMP peroxisome proliferator activated receptor signaling pathway
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0071333 ISS cellular response to glucose stimulus
GO:0071398 IMP cellular response to fatty acid
GO:0097411 IMP hypoxia-inducible factor-1alpha signaling pathway
GO:2000377 IMP regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000045748 Pdk3-001 protein_coding Mus_musculus 0 1576
ENSMUST00000134502 Pdk3-002 processed_transcript Mus_musculus 0 366

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