C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ferrochelatase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000382873 FECH-002 ENSG00000066926 9606 - 18:57549510-57586654 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000382873
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000382873 2.187±0.00 1.528±0.00 1.588±0.00 2.436±1.54 2.744±0.00 1.392±0.00 2.335±1.83 4.344±2.56 2.773±1.62 1.707±1.39 3.307±0.15 1.817±1.07 3.205±1.50 2.194±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006O8 CIL_0006O8_0001 CGP 18:57435685-57586772
CIL_0006O9 CIL_0006O9_0001 CGP 18:57548283-57622213

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004325 IDA:IEA ferrochelatase activity
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0006091 TAS generation of precursor metabolites and energy
GO:0006778 TAS porphyrin-containing compound metabolic process
GO:0006779 IEA porphyrin-containing compound biosynthetic process
GO:0006783 TAS:IEA heme biosynthetic process
GO:0008198 TAS ferrous iron binding
GO:0008203 IEA cholesterol metabolic process
GO:0009416 TAS response to light stimulus
GO:0009589 IEA detection of UV
GO:0010038 IEA response to metal ion
GO:0010288 IEA response to lead ion
GO:0010468 IEA regulation of gene expression
GO:0010999 IEA regulation of eIF2 alpha phosphorylation by heme
GO:0017085 IEA response to insecticide
GO:0020037 IEA heme binding
GO:0030218 IEA erythrocyte differentiation
GO:0030350 IEA iron-responsive element binding
GO:0034379 IEA very-low-density lipoprotein particle assembly
GO:0042493 IEA response to drug
GO:0044281 TAS small molecule metabolic process
GO:0045471 IEA response to ethanol
GO:0046501 IDA protoporphyrinogen IX metabolic process
GO:0046685 IEA response to arsenic-containing substance
GO:0046906 IEA tetrapyrrole binding
GO:0046984 IEA regulation of hemoglobin biosynthetic process
GO:0051537 IEA 2 iron, 2 sulfur cluster binding
GO:0051597 IEA response to methylmercury
GO:0055072 IEA iron ion homeostasis
GO:0070541 IEA response to platinum ion
GO:0071549 IEA cellular response to dexamethasone stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025484 Fech-201 protein_coding Mus_musculus 0 1389

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