C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000391748 LILRB2-001 ENSG00000131042 9606 - 19:54273821-54280883 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastHeartKidneyLiverOvaryPlacentaTestisENST00000391748
Transcript ID Adipose Adrenal Breast Heart Kidney Liver Ovary Placenta Testis
ENST00000391748 2.979±0.00 4.075±0.00 1.520±0.00 0.920±0.00 0.569±0.30 1.093±0.00 0.645±0.36 1.751±0.89 0.205±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005M6 CIL_0005M6_0001 CGP 19:54189938-54249003

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002578 IDA negative regulation of antigen processing and presentation
GO:0002666 IMP positive regulation of T cell tolerance induction
GO:0002767 IMP immune response-inhibiting cell surface receptor signaling pathway
GO:0002774 IDA Fc receptor mediated inhibitory signaling pathway
GO:0004872 TAS receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006955 TAS immune response
GO:0006968 TAS cellular defense response
GO:0007165 IMP signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0008157 IPI protein phosphatase 1 binding
GO:0009986 IDA cell surface
GO:0016020 TAS membrane
GO:0023029 IPI MHC class Ib protein binding
GO:0032396 IMP inhibitory MHC class I receptor activity
GO:0032755 NAS positive regulation of interleukin-6 production
GO:0034113 IDA heterotypic cell-cell adhesion
GO:0042102 IDA positive regulation of T cell proliferation
GO:0042130 IMP negative regulation of T cell proliferation
GO:0042288 IDA MHC class I protein binding
GO:0045591 IMP positive regulation of regulatory T cell differentiation
GO:0050776 TAS regulation of immune response
GO:0050839 IPI cell adhesion molecule binding
GO:0051926 IDA negative regulation of calcium ion transport
GO:0071222 IMP cellular response to lipopolysaccharide
GO:2001198 IC regulation of dendritic cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000120641 Gm15925-001 unprocessed_pseudogene Mus_musculus 0 267

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