C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: excision repair cross-complementation group 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000391945 ERCC2-001 ENSG00000104884 9606 - 19:45349837-45370618 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000391945
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000391945 1.309±0.00 2.486±0.00 0.320±0.00 3.740±0.00 2.621±0.00 0.729±0.00 1.145±0.00 5.571±0.00 1.720±1.61 1.787±0.00 1.180±0.00 2.777±1.89 2.193±0.18 4.242±2.10

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000439 IEA core TFIIH complex
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0001666 IEA response to hypoxia
GO:0001701 IEA in utero embryonic development
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0004672 IDA protein kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005675 TAS holo TFIIH complex
GO:0005737 IDA cytoplasm
GO:0005819 IDA spindle
GO:0006139 IEA nucleobase-containing compound metabolic process
GO:0006200 IEA ATP catabolic process
GO:0006281 TAS DNA repair
GO:0006283 IDA transcription-coupled nucleotide-excision repair
GO:0006289 NAS nucleotide-excision repair
GO:0006360 TAS transcription from RNA polymerase I promoter
GO:0006361 TAS transcription initiation from RNA polymerase I promoter
GO:0006362 TAS transcription elongation from RNA polymerase I promoter
GO:0006363 TAS termination of RNA polymerase I transcription
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0006468 IDA protein phosphorylation
GO:0006915 IMP apoptotic process
GO:0006979 IMP response to oxidative stress
GO:0007059 IMP chromosome segregation
GO:0007568 IEA aging
GO:0008022 IPI protein C-terminus binding
GO:0008026 IEA ATP-dependent helicase activity
GO:0008094 TAS DNA-dependent ATPase activity
GO:0008283 IEA cell proliferation
GO:0008353 IDA RNA polymerase II carboxy-terminal domain kinase activity
GO:0009411 IEA response to UV
GO:0009650 IGI UV protection
GO:0009791 IEA post-embryonic development
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016818 IEA hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0019907 IDA cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0021510 IEA spinal cord development
GO:0022405 IEA hair cycle process
GO:0030198 IEA extracellular matrix organization
GO:0030282 IEA bone mineralization
GO:0032289 IEA central nervous system myelin formation
GO:0032508 IEA DNA duplex unwinding
GO:0033683 IMP nucleotide-excision repair, DNA incision
GO:0035264 IEA multicellular organism growth
GO:0035315 IMP hair cell differentiation
GO:0040016 IEA embryonic cleavage
GO:0043139 IDA 5'-3' DNA helicase activity
GO:0043249 IEA erythrocyte maturation
GO:0043388 IEA positive regulation of DNA binding
GO:0043588 IEA skin development
GO:0044281 TAS small molecule metabolic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0047485 IPI protein N-terminus binding
GO:0048820 IEA hair follicle maturation
GO:0050434 TAS positive regulation of viral transcription
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0060218 IEA hematopoietic stem cell differentiation
GO:0071817 IDA MMXD complex
GO:1901990 IMP regulation of mitotic cell cycle phase transition

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000062831 Ercc2-001 protein_coding Mus_musculus 0 2861
ENSMUST00000108460 Ercc2-003 protein_coding Mus_musculus 0 2507
ENSMUST00000129249 Ercc2-004 protein_coding Mus_musculus 0 2139
ENSMUST00000108461 Ercc2-002 protein_coding Mus_musculus 0 1925
ENSMUST00000128167 Ercc2-007 processed_transcript Mus_musculus 0 800
ENSMUST00000127363 Ercc2-006 processed_transcript Mus_musculus 0 636
ENSMUST00000135693 Ercc2-009 retained_intron Mus_musculus 0 544
ENSMUST00000129291 Ercc2-008 retained_intron Mus_musculus 0 237
ENSMUST00000125246 Klc3-005 retained_intron Mus_musculus 6e-21 108
ENSMUST00000154419 Klc3-006 retained_intron Mus_musculus 6e-21 108
ENSMUST00000108457 Klc3-004 protein_coding Mus_musculus 1e-17 97
ENSMUST00000108459 Klc3-002 protein_coding Mus_musculus 1e-17 97
ENSMUST00000047170 Klc3-003 protein_coding Mus_musculus 1e-17 97
ENSMUST00000108458 Klc3-001 protein_coding Mus_musculus 1e-17 97

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