C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BCL2-like 11 (apoptosis facilitator)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000393256 BCL2L11-001 ENSG00000153094 9606 + 2:111120929-111168447 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonLiverLungOvaryPlacentaENST00000393256
Transcript ID Adipose Bladder Brain Breast Colon Liver Lung Ovary Placenta
ENST00000393256 1.230±0.00 0.436±0.00 0.439±0.00 0.781±0.00 0.540±0.00 0.333±0.02 0.865±0.17 1.121±0.16 0.402±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047S CIL_00047S_0001 CGP 2:110732573-111168447

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0001776 IEA leukocyte homeostasis
GO:0001782 IEA B cell homeostasis
GO:0001783 IEA B cell apoptotic process
GO:0001822 IEA kidney development
GO:0002260 IEA lymphocyte homeostasis
GO:0002262 IEA myeloid cell homeostasis
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005829 IDA cytosol
GO:0005874 IDA microtubule
GO:0006915 TAS apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007160 IEA cell-matrix adhesion
GO:0007283 IEA spermatogenesis
GO:0007420 IEA brain development
GO:0008017 IDA microtubule binding
GO:0008584 IEA male gonad development
GO:0008630 IDA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009791 IEA post-embryonic development
GO:0010942 IEA positive regulation of cell death
GO:0019898 IEA extrinsic component of membrane
GO:0030879 IEA mammary gland development
GO:0032464 IDA positive regulation of protein homooligomerization
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0035148 IEA tube formation
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0042981 IEA regulation of apoptotic process
GO:0043029 IEA T cell homeostasis
GO:0043065 IMP positive regulation of apoptotic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0043583 IEA ear development
GO:0045787 IEA positive regulation of cell cycle
GO:0046620 IEA regulation of organ growth
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048066 IEA developmental pigmentation
GO:0048070 IEA regulation of developmental pigmentation
GO:0048536 IEA spleen development
GO:0048538 IEA thymus development
GO:0048563 IEA post-embryonic organ morphogenesis
GO:0060139 IEA positive regulation of apoptotic process by virus
GO:0060154 IEA cellular process regulating host cell cycle in response to virus
GO:0070242 IEA thymocyte apoptotic process
GO:0090200 IMP positive regulation of release of cytochrome c from mitochondria
GO:0097140 IDA BIM-BCL-xl complex
GO:0097141 IDA BIM-BCL-2 complex
GO:0097190 TAS apoptotic signaling pathway
GO:0097192 IEA extrinsic apoptotic signaling pathway in absence of ligand
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1902110 IEA positive regulation of mitochondrial membrane permeability involved in apoptotic process
GO:1902263 IEA apoptotic process involved in embryonic digit morphogenesis
GO:2000271 IDA positive regulation of fibroblast apoptotic process
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000110341 Bcl2l11-001 protein_coding Mus_musculus 0 811
ENSMUST00000146023 Bcl2l11-002 processed_transcript Mus_musculus 0 682
ENSMUST00000019281 Bcl2l11-201 protein_coding Mus_musculus 0 327
ENSMUST00000103211 Bcl2l11-006 protein_coding Mus_musculus 0 327
ENSMUST00000103210 Bcl2l11-005 protein_coding Mus_musculus 0 327
ENSMUST00000089634 Bcl2l11-003 protein_coding Mus_musculus 0 327
ENSMUST00000129206 Bcl2l11-004 processed_transcript Mus_musculus 0 215
ENSMUST00000132201 Bcl2l11-007 processed_transcript Mus_musculus 0 193

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