C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: catenin (cadherin-associated protein), beta 1, 88kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000396185 CTNNB1-002 ENSG00000168036 9606 + 3:41199505-41240443 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000396185
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000396185 25.977±0.00 23.070±0.00 7.754±0.00 17.313±2.99 19.033±1.75 16.268±0.10 10.934±5.22 18.390±0.35 13.779±3.69 28.294±8.68 5.665±1.24 32.041±2.88 29.198±10.15 18.417±5.83

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000481 CIL_000481_0001 CGP 3:41194837-41962430

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IBA negative regulation of transcription from RNA polymerase II promoter
GO:0000578 IBA embryonic axis specification
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001569 IBA patterning of blood vessels
GO:0001658 IBA branching involved in ureteric bud morphogenesis
GO:0001702 IBA gastrulation with mouth forming second
GO:0001711 IBA endodermal cell fate commitment
GO:0001837 TAS epithelial to mesenchymal transition
GO:0001889 IBA liver development
GO:0003136 IBA negative regulation of heart induction by canonical Wnt signaling pathway
GO:0003337 IBA mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003713 IDA transcription coactivator activity
GO:0004871 NAS signal transducer activity
GO:0005198 IBA structural molecule activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005912 IDA adherens junction
GO:0005913 IDA cell-cell adherens junction
GO:0005915 IBA zonula adherens
GO:0005916 IBA fascia adherens
GO:0005925 IDA focal adhesion
GO:0005938 IDA cell cortex
GO:0006351 IEA transcription, DNA-templated
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0007016 IBA cytoskeletal anchoring at plasma membrane
GO:0007155 IMP cell adhesion
GO:0007160 IBA cell-matrix adhesion
GO:0007398 IBA ectoderm development
GO:0007403 IBA glial cell fate determination
GO:0008022 IPI protein C-terminus binding
GO:0008134 TAS transcription factor binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0009898 IBA cytoplasmic side of plasma membrane
GO:0009950 IBA dorsal/ventral axis specification
GO:0009954 IBA proximal/distal pattern formation
GO:0010718 IGI positive regulation of epithelial to mesenchymal transition
GO:0010909 IMP positive regulation of heparan sulfate proteoglycan biosynthetic process
GO:0014010 IBA Schwann cell proliferation
GO:0016020 ISS membrane
GO:0016055 IDA Wnt signaling pathway
GO:0016328 IDA lateral plasma membrane
GO:0016337 IMP single organismal cell-cell adhesion
GO:0016342 IDA catenin complex
GO:0019899 IPI enzyme binding
GO:0019900 IPI kinase binding
GO:0019901 IBA protein kinase binding
GO:0019903 IPI protein phosphatase binding
GO:0022009 IBA central nervous system vasculogenesis
GO:0030018 IBA Z disc
GO:0030027 IBA lamellipodium
GO:0030054 TAS cell junction
GO:0030057 IBA desmosome
GO:0030326 IBA embryonic limb morphogenesis
GO:0030331 IPI estrogen receptor binding
GO:0030521 NAS androgen receptor signaling pathway
GO:0030539 IBA male genitalia development
GO:0030877 IDA beta-catenin destruction complex
GO:0030902 IBA hindbrain development
GO:0030997 IDA regulation of centriole-centriole cohesion
GO:0031016 IBA pancreas development
GO:0031069 IBA hair follicle morphogenesis
GO:0031528 IBA microvillus membrane
GO:0032331 IBA negative regulation of chondrocyte differentiation
GO:0032355 IDA response to estradiol
GO:0032481 TAS positive regulation of type I interferon production
GO:0032993 IDA protein-DNA complex
GO:0033077 IBA T cell differentiation in thymus
GO:0033234 IDA negative regulation of protein sumoylation
GO:0034333 IMP adherens junction assembly
GO:0034394 IMP protein localization to cell surface
GO:0035257 IPI nuclear hormone receptor binding
GO:0035315 TAS hair cell differentiation
GO:0036023 ISS embryonic skeletal limb joint morphogenesis
GO:0042129 IBA regulation of T cell proliferation
GO:0042475 IBA odontogenesis of dentin-containing tooth
GO:0042493 IEP response to drug
GO:0042692 TAS muscle cell differentiation
GO:0043065 IDA positive regulation of apoptotic process
GO:0043123 IBA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043198 IBA dendritic shaft
GO:0043410 IBA positive regulation of MAPK cascade
GO:0043587 IBA tongue morphogenesis
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044325 IPI ion channel binding
GO:0044334 IMP canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
GO:0044336 IMP canonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0045087 TAS innate immune response
GO:0045202 IBA synapse
GO:0045294 IPI alpha-catenin binding
GO:0045296 IPI cadherin binding
GO:0045669 IBA positive regulation of osteoblast differentiation
GO:0045671 IBA negative regulation of osteoclast differentiation
GO:0045743 IBA positive regulation of fibroblast growth factor receptor signaling pathway
GO:0045765 TAS regulation of angiogenesis
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IPI SMAD binding
GO:0048145 TAS regulation of fibroblast proliferation
GO:0048262 IBA determination of dorsal/ventral asymmetry
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048489 IBA synaptic vesicle transport
GO:0048538 IBA thymus development
GO:0048599 IBA oocyte development
GO:0048617 IBA embryonic foregut morphogenesis
GO:0048660 IMP regulation of smooth muscle cell proliferation
GO:0050681 NAS androgen receptor binding
GO:0050808 IBA synapse organization
GO:0051145 IBA smooth muscle cell differentiation
GO:0051149 TAS positive regulation of muscle cell differentiation
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060440 IBA trachea formation
GO:0060479 IBA lung cell differentiation
GO:0060484 IBA lung-associated mesenchyme development
GO:0060492 IBA lung induction
GO:0060769 IBA positive regulation of epithelial cell proliferation involved in prostate gland development
GO:0060789 IBA hair follicle placode formation
GO:0060916 IBA mesenchymal cell proliferation involved in lung development
GO:0061047 IBA positive regulation of branching involved in lung morphogenesis
GO:0061154 IMP endothelial tube morphogenesis
GO:0061324 ISS canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
GO:0070062 IDA extracellular vesicular exosome
GO:0070369 IDA beta-catenin-TCF7L2 complex
GO:0070411 IPI I-SMAD binding
GO:0070412 IPI R-SMAD binding
GO:0070602 IMP regulation of centromeric sister chromatid cohesion
GO:0071363 IMP cellular response to growth factor stimulus
GO:0071681 IDA cellular response to indole-3-methanol
GO:0071944 IDA cell periphery
GO:0072033 IBA renal vesicle formation
GO:0072053 IBA renal inner medulla development
GO:0072054 IBA renal outer medulla development
GO:0072079 IBA nephron tubule formation
GO:0072182 ISS regulation of nephron tubule epithelial cell differentiation
GO:0090279 IDA regulation of calcium ion import
GO:2000008 IDA regulation of protein localization to cell surface

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000178812 Ctnnb1-201 protein_coding Mus_musculus 0 3136
ENSMUST00000007130 Ctnnb1-001 protein_coding Mus_musculus 0 3136
ENSMUST00000154356 Ctnnb1-002 nonsense_mediated_decay Mus_musculus 0 3131
ENSMUST00000163844 Ctnnb1-011 nonsense_mediated_decay Mus_musculus 0 2676
ENSMUST00000154687 Ctnnb1-003 retained_intron Mus_musculus 0 2174
ENSMUST00000156911 Ctnnb1-010 processed_transcript Mus_musculus 0 1024
ENSMUST00000133689 Ctnnb1-009 protein_coding Mus_musculus 0 684
ENSMUST00000126633 Ctnnb1-007 processed_transcript Mus_musculus 0 640
ENSMUST00000169931 Ctnnb1-005 protein_coding Mus_musculus 0 634
ENSMUST00000170729 Ctnnb1-013 nonsense_mediated_decay Mus_musculus 0 566
ENSMUST00000139138 Ctnnb1-008 retained_intron Mus_musculus 0 453
ENSMUST00000170406 Ulk4-004 processed_transcript Mus_musculus 0 337

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