C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: discs, large homolog 4 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000399506 DLG4-002 ENSG00000132535 9606 - 17:7189890-7217339 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonLiverTestisENST00000399506
Transcript ID Brain Colon Liver Testis
ENST00000399506 51.850±31.57 13.064±0.00 1.912±0.00 17.392±1.26

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002091 ISS negative regulation of receptor internalization
GO:0005515 IPI:IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005783 ISS endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0006461 IDA protein complex assembly
GO:0007165 TAS signal transduction
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0007268 TAS synaptic transmission
GO:0007399 TAS nervous system development
GO:0007411 TAS axon guidance
GO:0007612 TAS learning
GO:0008021 ISS synaptic vesicle
GO:0008022 IPI protein C-terminus binding
GO:0008328 ISS ionotropic glutamate receptor complex
GO:0014069 ISS postsynaptic density
GO:0016188 ISS synaptic vesicle maturation
GO:0019903 ISS protein phosphatase binding
GO:0030054 ISS cell junction
GO:0030165 ISS PDZ domain binding
GO:0030666 TAS endocytic vesicle membrane
GO:0030863 IDA cortical cytoskeleton
GO:0031234 ISS extrinsic component of cytoplasmic side of plasma membrane
GO:0031697 ISS beta-1 adrenergic receptor binding
GO:0031748 ISS D1 dopamine receptor binding
GO:0031812 ISS P2Y1 nucleotide receptor binding
GO:0032281 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0032403 ISS protein complex binding
GO:0032839 ISS dendrite cytoplasm
GO:0033130 ISS acetylcholine receptor binding
GO:0035255 ISS ionotropic glutamate receptor binding
GO:0035418 IDA protein localization to synapse
GO:0043197 ISS dendritic spine
GO:0044224 ISS juxtaparanode region of axon
GO:0044306 ISS neuron projection terminus
GO:0044309 ISS neuron spine
GO:0045184 IDA establishment of protein localization
GO:0045202 IDA synapse
GO:0045211 IDA postsynaptic membrane
GO:0048169 ISS regulation of long-term neuronal synaptic plasticity
GO:0050806 ISS positive regulation of synaptic transmission
GO:0060076 ISS excitatory synapse
GO:0060997 ISS dendritic spine morphogenesis
GO:0097110 ISS scaffold protein binding
GO:0097113 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering
GO:0097120 ISS receptor localization to synapse
GO:0097481 ISS neuronal postsynaptic density
GO:2000310 ISS regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018700 Dlg4-003 protein_coding Mus_musculus 0 4392
ENSMUST00000108588 Dlg4-001 protein_coding Mus_musculus 0 4335
ENSMUST00000108589 Dlg4-002 protein_coding Mus_musculus 0 4041
ENSMUST00000132597 Dlg4-006 protein_coding Mus_musculus 0 1057
ENSMUST00000123687 Dlg4-012 nonsense_mediated_decay Mus_musculus 0 870
ENSMUST00000133140 Dlg4-004 protein_coding Mus_musculus 0 706
ENSMUST00000138004 Dlg4-011 retained_intron Mus_musculus 0 556
ENSMUST00000124568 Dlg4-008 protein_coding Mus_musculus 0 555
ENSMUST00000135916 Dlg4-009 protein_coding Mus_musculus 0 496
ENSMUST00000134376 Dlg4-005 protein_coding Mus_musculus 0 462
ENSMUST00000131497 Dlg4-007 retained_intron Mus_musculus 0 333
ENSMUST00000143920 Dlg4-010 protein_coding Mus_musculus 0 248
ENSMUST00000108586 Dlg4-013 processed_transcript Mus_musculus 2e-25 122

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