C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: discs, large homolog 4 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000108588 Dlg4-001 ENSMUSG00000020886 10090 + 11:70018466-70045532 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000108588
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000108588 1.023±0.01 1.493±0.00 24.067±12.66 0.925±0.00 0.670±0.14 0.259±0.00 0.297±0.00 0.200±0.13 0.262±0.13 2.791±0.59 0.411±0.00 0.281±0.13

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002091 ISS negative regulation of receptor internalization
GO:0005198 NAS structural molecule activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0006461 ISS protein complex assembly
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0007626 NAS locomotory behavior
GO:0008021 IDA synaptic vesicle
GO:0008022 ISS protein C-terminus binding
GO:0008328 IDA ionotropic glutamate receptor complex
GO:0014069 IDA:ISS postsynaptic density
GO:0016020 IDA membrane
GO:0016188 IDA synaptic vesicle maturation
GO:0019903 ISS protein phosphatase binding
GO:0030054 IDA cell junction
GO:0030165 ISS PDZ domain binding
GO:0030425 IDA dendrite
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0031697 ISS beta-1 adrenergic receptor binding
GO:0031748 ISS D1 dopamine receptor binding
GO:0031812 ISS P2Y1 nucleotide receptor binding
GO:0032281 IDA alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0032403 ISS protein complex binding
GO:0032839 ISS dendrite cytoplasm
GO:0033130 ISS acetylcholine receptor binding
GO:0035176 IMP social behavior
GO:0035255 IPI ionotropic glutamate receptor binding
GO:0035418 IDA:ISS protein localization to synapse
GO:0035641 IMP locomotory exploration behavior
GO:0042043 NAS neurexin family protein binding
GO:0042220 NAS response to cocaine
GO:0043197 IDA dendritic spine
GO:0044224 IDA juxtaparanode region of axon
GO:0044300 IDA cerebellar mossy fiber
GO:0044306 IDA neuron projection terminus
GO:0044309 IDA neuron spine
GO:0045184 ISS establishment of protein localization
GO:0045202 IDA synapse
GO:0045211 IDA postsynaptic membrane
GO:0048168 NAS regulation of neuronal synaptic plasticity
GO:0048169 IGI regulation of long-term neuronal synaptic plasticity
GO:0050806 ISS positive regulation of synaptic transmission
GO:0050885 IMP neuromuscular process controlling balance
GO:0060076 IDA excitatory synapse
GO:0060997 IDA dendritic spine morphogenesis
GO:0071625 IMP vocalization behavior
GO:0097060 IDA synaptic membrane
GO:0097110 IPI scaffold protein binding
GO:0097113 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering
GO:0097120 ISS receptor localization to synapse
GO:0097481 IDA:ISS neuronal postsynaptic density
GO:2000310 ISS regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential
GO:2000821 IMP regulation of grooming behavior

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000302955 DLG4-003 protein_coding Homo_sapiens 0 4375
ENST00000399506 DLG4-002 protein_coding Homo_sapiens 0 4335
ENST00000399510 DLG4-001 protein_coding Homo_sapiens 0 3984
ENST00000447163 DLG4-007 protein_coding Homo_sapiens 0 739
ENST00000451807 DLG4-006 protein_coding Homo_sapiens 0 894
ENST00000485100 DLG4-004 protein_coding Homo_sapiens 0 1247
ENST00000486626 DLG4-009 protein_coding Homo_sapiens 0 582
ENST00000489885 DLG4-005 retained_intron Homo_sapiens 0 1164
ENST00000491753 DLG4-011 nonsense_mediated_decay Homo_sapiens 0 785
ENST00000493294 DLG4-008 protein_coding Homo_sapiens 0 523
ENST00000543245 ACADVL-007 protein_coding Homo_sapiens 0.000000000000001 90

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