C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FK506 binding protein 1A, 12kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000400137 FKBP1A-001 ENSG00000088832 9606 - 20:1368978-1393162 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000400137
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000400137 88.142±0.00 72.551±0.00 1.914±0.00 23.699±1.83 46.750±0.00 30.520±15.53 20.075±17.73 21.166±14.82 17.433±0.00 102.409±83.40 14.803±5.81 37.430±30.75 151.856±0.92 35.485±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000413 IDA protein peptidyl-prolyl isomerization
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0003007 ISS heart morphogenesis
GO:0003755 TAS peptidyl-prolyl cis-trans isomerase activity
GO:0004871 IMP signal transducer activity
GO:0005024 TAS transforming growth factor beta-activated receptor activity
GO:0005160 ISS transforming growth factor beta receptor binding
GO:0005219 TAS ryanodine-sensitive calcium-release channel activity
GO:0005515 IPI protein binding
GO:0005527 NAS macrolide binding
GO:0005528 NAS FK506 binding
GO:0005737 IDA cytoplasm
GO:0005789 IBA endoplasmic reticulum membrane
GO:0005829 IDA cytosol
GO:0006457 NAS:IEA protein folding
GO:0006458 TAS 'de novo' protein folding
GO:0006936 IEA muscle contraction
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007183 IDA SMAD protein complex assembly
GO:0008144 IEA drug binding
GO:0010039 IEA response to iron ion
GO:0014802 ISS terminal cisterna
GO:0016020 IDA membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019899 IEA enzyme binding
GO:0022417 TAS protein maturation by protein folding
GO:0030018 IDA Z disc
GO:0030544 IEA Hsp70 protein binding
GO:0031000 IEA response to caffeine
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0032092 IDA positive regulation of protein binding
GO:0032513 IDA negative regulation of protein phosphatase type 2B activity
GO:0032880 IGI regulation of protein localization
GO:0032925 IDA regulation of activin receptor signaling pathway
GO:0033017 IEA sarcoplasmic reticulum membrane
GO:0034713 ISS type I transforming growth factor beta receptor binding
GO:0042026 TAS protein refolding
GO:0042098 IEA T cell proliferation
GO:0042110 NAS T cell activation
GO:0042803 IEA protein homodimerization activity
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043206 IDA extracellular fibril organization
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043679 IEA axon terminus
GO:0044325 ISS ion channel binding
GO:0046332 IPI SMAD binding
GO:0048185 IPI activin binding
GO:0050776 IMP regulation of immune response
GO:0051209 IEA release of sequestered calcium ion into cytosol
GO:0055010 ISS ventricular cardiac muscle tissue morphogenesis
GO:0060314 ISS regulation of ryanodine-sensitive calcium-release channel activity
GO:0060347 ISS heart trabecula formation
GO:0061077 IBA chaperone-mediated protein folding
GO:0070062 IDA extracellular vesicular exosome
GO:0070588 NAS calcium ion transmembrane transport
GO:1902991 IGI regulation of amyloid precursor protein catabolic process
GO:1990000 IDA amyloid fibril formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000044011 Fkbp1a-001 protein_coding Mus_musculus 0 1382
ENSMUST00000142271 Fkbp1a-002 protein_coding Mus_musculus 0 1232
ENSMUST00000143230 Fkbp1a-005 processed_transcript Mus_musculus 0 654
ENSMUST00000142985 Fkbp1a-003 processed_transcript Mus_musculus 0 616
ENSMUST00000148295 Fkbp1a-010 retained_intron Mus_musculus 0 544
ENSMUST00000148978 Fkbp1a-008 processed_transcript Mus_musculus 0 510
ENSMUST00000132614 Fkbp1a-007 processed_transcript Mus_musculus 0 483
ENSMUST00000137597 Fkbp1a-004 processed_transcript Mus_musculus 0 396
ENSMUST00000144171 Fkbp1a-006 processed_transcript Mus_musculus 3e-35 154
ENSMUST00000126670 Fkbp1a-009 retained_intron Mus_musculus 1e-34 152

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