C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MAP-kinase activating death domain
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000406482 MADD-003 ENSG00000110514 9606 + 11:47269674-47330031 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonMuscleOvaryPlacentaENST00000406482
Transcript ID Bladder Brain Colon Muscle Ovary Placenta
ENST00000406482 0.705±0.00 4.815±0.00 1.119±0.00 1.948±0.00 1.533±0.00 1.384±0.22

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IMP activation of MAPK activity
GO:0005123 TAS death receptor binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007166 TAS cell surface receptor signaling pathway
GO:0016021 IDA integral component of membrane
GO:0017112 IDA Rab guanyl-nucleotide exchange factor activity
GO:0030295 TAS protein kinase activator activity
GO:0032483 IDA regulation of Rab protein signal transduction
GO:0032851 IDA positive regulation of Rab GTPase activity
GO:0042981 IMP regulation of apoptotic process
GO:0051726 IMP regulation of cell cycle
GO:0097194 IMP execution phase of apoptosis
GO:1902041 IMP regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001236 IDA regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000111369 Madd-008 protein_coding Mus_musculus 0 5799
ENSMUST00000111373 Madd-009 protein_coding Mus_musculus 0 5552
ENSMUST00000111375 Madd-007 protein_coding Mus_musculus 0 3179
ENSMUST00000099725 Madd-202 protein_coding Mus_musculus 0 2839
ENSMUST00000066473 Madd-201 protein_coding Mus_musculus 0 2839
ENSMUST00000066420 Madd-013 protein_coding Mus_musculus 0 2839
ENSMUST00000130395 Madd-014 retained_intron Mus_musculus 0 2839
ENSMUST00000111372 Madd-003 protein_coding Mus_musculus 0 2839
ENSMUST00000111381 Madd-002 protein_coding Mus_musculus 0 2839
ENSMUST00000077941 Madd-001 protein_coding Mus_musculus 0 2839
ENSMUST00000099723 Madd-010 protein_coding Mus_musculus 0 2839
ENSMUST00000111376 Madd-011 protein_coding Mus_musculus 0 2839
ENSMUST00000111370 Madd-006 protein_coding Mus_musculus 0 2839
ENSMUST00000075269 Madd-005 protein_coding Mus_musculus 0 2713
ENSMUST00000111371 Madd-004 protein_coding Mus_musculus 0 2713
ENSMUST00000125227 Madd-025 processed_transcript Mus_musculus 0 2712
ENSMUST00000153688 Madd-024 processed_transcript Mus_musculus 0 2712
ENSMUST00000125321 Madd-023 processed_transcript Mus_musculus 0 2712
ENSMUST00000150461 Madd-022 processed_transcript Mus_musculus 0 2712
ENSMUST00000154028 Madd-012 processed_transcript Mus_musculus 0 2712
ENSMUST00000130591 Madd-019 retained_intron Mus_musculus 0 863
ENSMUST00000140600 Madd-017 protein_coding Mus_musculus 0 582
ENSMUST00000135910 Madd-026 retained_intron Mus_musculus 0 392
ENSMUST00000146097 Madd-018 retained_intron Mus_musculus 0 276
ENSMUST00000156368 Madd-021 retained_intron Mus_musculus 5e-33 148

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