C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nemo-like kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000407008 NLK-001 ENSG00000087095 9606 + 17:28042156-28196381 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000407008
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000407008 4.997±0.00 2.312±0.00 2.283±0.00 13.451±0.34 3.016±0.31 1.325±0.54 2.802±1.04 3.582±2.12 1.777±0.61 2.907±0.45 1.026±0.54 2.521±0.31 2.739±0.30 4.779±0.14

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000287 ISS magnesium ion binding
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004707 IEA:ISS MAP kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0006468 ISS:IEA protein phosphorylation
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0008134 IPI transcription factor binding
GO:0016055 IEA Wnt signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018107 ISS peptidyl-threonine phosphorylation
GO:0030178 ISS negative regulation of Wnt signaling pathway
GO:0031625 IPI ubiquitin protein ligase binding
GO:0033136 ISS serine phosphorylation of STAT3 protein
GO:0035556 ISS intracellular signal transduction
GO:0042169 ISS SH2 domain binding
GO:0046777 IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000142739 Nlk-001 protein_coding Mus_musculus 0 5227
ENSMUST00000165271 Nlk-002 retained_intron Mus_musculus 0 1275
ENSMUST00000120843 Nlk-ps1-001 processed_pseudogene Mus_musculus 0 1127
ENSMUST00000165475 Nlk-004 processed_transcript Mus_musculus 0 784
ENSMUST00000170394 Nlk-003 protein_coding Mus_musculus 0 510

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