C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: endothelin converting enzyme 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000415912 ECE1-001 ENSG00000117298 9606 - 1:21217247-21345504 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000415912
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000415912 56.131±0.00 16.966±0.00 0.429±0.00 7.781±0.00 20.987±0.00 19.123±0.00 6.347±5.34 9.123±0.00 7.747±4.31 43.183±0.00 4.655±0.00 23.419±15.45 23.415±7.42 9.938±5.84

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002W8 CIL_0002W8_0002 CGP 1:20806292-21345504

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001921 IMP positive regulation of receptor recycling
GO:0003100 IC regulation of systemic arterial blood pressure by endothelin
GO:0004175 IDA endopeptidase activity
GO:0004222 IEA:ISS metalloendopeptidase activity
GO:0005765 IDA lysosomal membrane
GO:0005768 IDA endosome
GO:0005769 IDA early endosome
GO:0005886 IDA plasma membrane
GO:0006508 IEA proteolysis
GO:0007507 IMP heart development
GO:0009897 IDA external side of plasma membrane
GO:0010814 IDA substance P catabolic process
GO:0010815 IDA bradykinin catabolic process
GO:0010816 IDA calcitonin catabolic process
GO:0016020 IDA membrane
GO:0016021 IDA integral component of membrane
GO:0016485 IEA:IDA protein processing
GO:0016486 IDA peptide hormone processing
GO:0017046 IC peptide hormone binding
GO:0019229 IC regulation of vasoconstriction
GO:0031302 TAS intrinsic component of endosome membrane
GO:0031982 ISS vesicle
GO:0033093 IDA Weibel-Palade body
GO:0034959 IDA endothelin maturation
GO:0042447 IDA hormone catabolic process
GO:0042733 IMP embryonic digit morphogenesis
GO:0042803 IPI protein homodimerization activity
GO:0043583 IMP ear development
GO:0046872 IEA metal ion binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102518 Ece1-001 protein_coding Mus_musculus 0 2832
ENSMUST00000151110 Ece1-003 protein_coding Mus_musculus 0 664

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