C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: myeloid differentiation primary response 88
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000417037 MYD88-201 ENSG00000172936 9606 + 3:38138478-38143019 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002238 IEA response to molecule of fungal origin
GO:0002755 IEA MyD88-dependent toll-like receptor signaling pathway
GO:0005102 IEA receptor binding
GO:0005121 IEA Toll binding
GO:0005149 IEA interleukin-1 receptor binding
GO:0005515 IEA protein binding
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0007165 IEA signal transduction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007254 IEA JNK cascade
GO:0008063 IEA Toll signaling pathway
GO:0009615 IEA response to virus
GO:0014069 IEA postsynaptic density
GO:0016064 IEA immunoglobulin mediated immune response
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0032494 IEA response to peptidoglycan
GO:0032496 IEA response to lipopolysaccharide
GO:0032740 IEA positive regulation of interleukin-17 production
GO:0032747 IEA positive regulation of interleukin-23 production
GO:0032755 IEA positive regulation of interleukin-6 production
GO:0032760 IEA positive regulation of tumor necrosis factor production
GO:0042127 IEA regulation of cell proliferation
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043234 IEA protein complex
GO:0044130 IEA negative regulation of growth of symbiont in host
GO:0045080 IEA positive regulation of chemokine biosynthetic process
GO:0045351 IEA type I interferon biosynthetic process
GO:0046330 IEA positive regulation of JNK cascade
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0050671 IEA positive regulation of lymphocyte proliferation
GO:0050727 IEA regulation of inflammatory response
GO:0050830 IEA defense response to Gram-positive bacterium
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0070976 IEA TIR domain binding
GO:0090557 IEA establishment of endothelial intestinal barrier

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000035092 Myd88-001 protein_coding Mus_musculus 0 678
ENSMUST00000150837 Myd88-002 retained_intron Mus_musculus 0 309

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