C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pyruvate dehydrogenase (lipoamide) alpha 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000422285 PDHA1-004 ENSG00000131828 9606 + X:19343933-19361685 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000422285
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000422285 3.899±0.00 4.806±0.00 3.808±0.00 6.299±0.59 10.661±0.00 3.273±1.37 16.567±5.96 8.337±3.24 3.595±0.74 2.295±0.52 4.833±0.00 4.338±2.32 3.841±0.60 4.506±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004738 IDA pyruvate dehydrogenase activity
GO:0004739 IEA pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006006 IEA glucose metabolic process
GO:0006086 IDA acetyl-CoA biosynthetic process from pyruvate
GO:0006090 TAS pyruvate metabolic process
GO:0006096 IEA glycolytic process
GO:0006099 IDA tricarboxylic acid cycle
GO:0008152 IEA metabolic process
GO:0010510 TAS regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0016624 IEA oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045254 IDA pyruvate dehydrogenase complex
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033662 Pdha1-001 protein_coding Mus_musculus 0 1432
ENSMUST00000163084 4930519F09Rik-001 transcribed_processed_pseudogene Mus_musculus 0 1070
ENSMUST00000126440 Pdha1-004 retained_intron Mus_musculus 0 603

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