C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitochondrial antiviral signaling protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000428216 MAVS-001 ENSG00000088888 9606 + 20:3846843-3876110 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000428216
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000428216 14.364±0.00 10.736±0.00 2.986±0.00 3.249±2.33 8.950±5.78 7.442±2.43 6.543±5.05 6.636±4.44 3.294±0.29 3.705±1.30 12.987±7.98 8.279±3.44 5.747±2.14 3.401±2.81

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00034V CIL_00034V_0001 CGP 20:3820524-3876123
CIL_00067O CIL_00067O_0002 CGP 20:3846799-3929882

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0002218 IMP activation of innate immune response
GO:0002230 IDA positive regulation of defense response to virus by host
GO:0004871 IMP signal transducer activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005741 IDA mitochondrial outer membrane
GO:0005777 IEA peroxisome
GO:0005778 IDA peroxisomal membrane
GO:0007165 IMP signal transduction
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0019901 IPI protein kinase binding
GO:0031966 IDA mitochondrial membrane
GO:0032480 TAS negative regulation of type I interferon production
GO:0032481 IEA positive regulation of type I interferon production
GO:0032727 IDA positive regulation of interferon-alpha production
GO:0032728 IDA positive regulation of interferon-beta production
GO:0032757 IDA positive regulation of interleukin-8 production
GO:0032760 IDA positive regulation of tumor necrosis factor production
GO:0033160 IDA positive regulation of protein import into nucleus, translocation
GO:0039529 IEA RIG-I signaling pathway
GO:0042742 IMP defense response to bacterium
GO:0042993 IDA positive regulation of transcription factor import into nucleus
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045071 IDA negative regulation of viral genome replication
GO:0045087 IMP innate immune response
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050700 IPI CARD domain binding
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051607 IDA defense response to virus
GO:0060340 IDA positive regulation of type I interferon-mediated signaling pathway
GO:0071360 IMP cellular response to exogenous dsRNA
GO:0071651 IDA positive regulation of chemokine (C-C motif) ligand 5 production
GO:0071660 IDA positive regulation of IP-10 production
GO:1900063 IMP regulation of peroxisome organization

Homologs

No Homologs available.

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