C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: major histocompatibility complex, class I, F
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000434407 HLA-F-002 ENSG00000204642 9606 + 6:29723464-29726526 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderLungOvaryPlacentaTestisENST00000434407
Transcript ID Bladder Lung Ovary Placenta Testis
ENST00000434407 1.440±0.00 8.249±0.00 55.790±0.00 12.300±0.00 5.358±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000420 CIL_000420_0003 CGP 6:29722775-29831125

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 IEA:TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0005783 IDA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IDA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0031901 TAS early endosome membrane
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 IEA peptide antigen binding
GO:0042612 IEA MHC class I protein complex
GO:0046978 IPI TAP1 binding
GO:0046979 IPI TAP2 binding
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000174839 H2-T23-002 retained_intron Mus_musculus 0 272
ENSMUST00000102678 H2-T23-001 protein_coding Mus_musculus 0 272
ENSMUST00000174471 H2-T23-005 retained_intron Mus_musculus 4e-31 139
ENSMUST00000174161 H2-T23-003 retained_intron Mus_musculus 4e-31 139

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