C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: allograft inflammatory factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000440907 AIF1-001 ENSG00000235588 9606 + CHR_HSCHR6_MHC_SSTO_CTG1:31605935-31607772 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001774 NAS microglial cell activation
GO:0001891 ISS phagocytic cup
GO:0003674 ND molecular_function
GO:0005509 ISS:IEA calcium ion binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005829 IDA cytosol
GO:0005884 IDA actin filament
GO:0006911 ISS phagocytosis, engulfment
GO:0006954 ISS inflammatory response
GO:0016601 ISS Rac protein signal transduction
GO:0030027 ISS lamellipodium
GO:0030041 IDA actin filament polymerization
GO:0032587 IDA ruffle membrane
GO:0042102 IDA positive regulation of T cell proliferation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048661 IDA positive regulation of smooth muscle cell proliferation
GO:0048662 IDA negative regulation of smooth muscle cell proliferation
GO:0051015 IDA actin filament binding
GO:0051017 IDA actin filament bundle assembly
GO:0071346 ISS cellular response to interferon-gamma
GO:0071672 IDA negative regulation of smooth muscle cell chemotaxis
GO:0071673 IDA positive regulation of smooth muscle cell chemotaxis
GO:0090026 IDA positive regulation of monocyte chemotaxis
GO:0097178 ISS ruffle assembly
GO:1900087 IDA positive regulation of G1/S transition of mitotic cell cycle
GO:2000406 IDA positive regulation of T cell migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025257 Aif1-002 protein_coding Mus_musculus 0 569
ENSMUST00000173324 Aif1-001 protein_coding Mus_musculus 0 569
ENSMUST00000172693 Aif1-003 protein_coding Mus_musculus 0 569
ENSMUST00000172679 Aif1-004 processed_transcript Mus_musculus 0 525
ENSMUST00000173106 Aif1-006 protein_coding Mus_musculus 0 226
ENSMUST00000138833 Aif1l-004 processed_transcript Mus_musculus 3e-22 110
ENSMUST00000001920 Aif1l-001 protein_coding Mus_musculus 3e-22 110
ENSMUST00000156743 Aif1l-007 processed_transcript Mus_musculus 2e-19 100
ENSMUST00000128271 Aif1l-005 processed_transcript Mus_musculus 2e-19 100
ENSMUST00000125457 Aif1l-006 processed_transcript Mus_musculus 3e-16 90

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