C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: allograft inflammatory factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000173324 Aif1-001 ENSMUSG00000024397 10090 - 17:35170992-35176001 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartKidneyTestisENSMUST00000173324
Transcript ID Heart Kidney Testis
ENSMUST00000173324 1.078±0.00 0.314±0.00 97.620±40.86

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0001774 NAS microglial cell activation
GO:0001891 IDA phagocytic cup
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 ISS cytosol
GO:0005884 IDA actin filament
GO:0006911 IMP phagocytosis, engulfment
GO:0006954 ISS inflammatory response
GO:0010629 IEA negative regulation of gene expression
GO:0014739 IEA positive regulation of muscle hyperplasia
GO:0016601 IMP Rac protein signal transduction
GO:0030027 IDA lamellipodium
GO:0030041 ISS actin filament polymerization
GO:0030335 IEA positive regulation of cell migration
GO:0031668 IEA cellular response to extracellular stimulus
GO:0032587 IDA ruffle membrane
GO:0032870 IEA cellular response to hormone stimulus
GO:0034097 IEA response to cytokine
GO:0042102 ISS positive regulation of T cell proliferation
GO:0042995 IEA cell projection
GO:0043066 IEA negative regulation of apoptotic process
GO:0043204 IEA perikaryon
GO:0045429 IEA positive regulation of nitric oxide biosynthetic process
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048661 ISS positive regulation of smooth muscle cell proliferation
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0048678 IEA response to axon injury
GO:0051015 ISS actin filament binding
GO:0051017 ISS actin filament bundle assembly
GO:0051602 IEA response to electrical stimulus
GO:0071315 IEA cellular response to morphine
GO:0071346 ISS cellular response to interferon-gamma
GO:0071447 IEA cellular response to hydroperoxide
GO:0071672 IEA negative regulation of smooth muscle cell chemotaxis
GO:0071673 ISS positive regulation of smooth muscle cell chemotaxis
GO:0090026 ISS positive regulation of monocyte chemotaxis
GO:0097178 IMP ruffle assembly
GO:1900087 ISS positive regulation of G1/S transition of mitotic cell cycle
GO:2000406 ISS positive regulation of T cell migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000337917 AIF1-004 protein_coding Homo_sapiens 0 525
ENST00000376059 AIF1-001 protein_coding Homo_sapiens 0 569
ENST00000383474 AIF1-001 protein_coding Homo_sapiens 0 569
ENST00000412407 AIF1-004 protein_coding Homo_sapiens 0 525
ENST00000413349 AIF1-001 protein_coding Homo_sapiens 0 569
ENST00000414149 AIF1-001 protein_coding Homo_sapiens 0 569
ENST00000417200 AIF1-004 protein_coding Homo_sapiens 0 525
ENST00000425748 AIF1-001 protein_coding Homo_sapiens 0 569
ENST00000437985 AIF1-004 protein_coding Homo_sapiens 0 525
ENST00000440907 AIF1-001 protein_coding Homo_sapiens 0 569
ENST00000454372 AIF1-004 protein_coding Homo_sapiens 0 525
ENST00000454573 AIF1-004 protein_coding Homo_sapiens 0 525
ENST00000459762 AIF1-006 retained_intron Homo_sapiens 0 230
ENST00000462008 AIF1-003 retained_intron Homo_sapiens 5.60519e-45 185
ENST00000466820 AIF1-006 retained_intron Homo_sapiens 0 230
ENST00000468277 AIF1-006 retained_intron Homo_sapiens 0 230
ENST00000469692 AIF1-003 retained_intron Homo_sapiens 5.60519e-45 185
ENST00000470803 AIF1-006 retained_intron Homo_sapiens 0 230
ENST00000486737 AIF1-003 retained_intron Homo_sapiens 5.60519e-45 185
ENST00000488491 AIF1-003 processed_transcript Homo_sapiens 5.60519e-45 185
ENST00000489150 AIF1-003 retained_intron Homo_sapiens 5.60519e-45 185
ENST00000489685 AIF1-006 retained_intron Homo_sapiens 0 230
ENST00000495860 AIF1-006 retained_intron Homo_sapiens 0 230
ENST00000497362 AIF1-003 retained_intron Homo_sapiens 5.60519e-45 185

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