C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: sprouty-related, EVH1 domain containing 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000443619 SPRED2-008 ENSG00000198369 9606 - 2:65312993-65366650 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartLiverENST00000443619
Transcript ID Heart Liver
ENST00000443619 0.300±0.00 0.802±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002N3 CIL_0002N3_0002 CGP 2:65227753-65432637

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000188 ISS inactivation of MAPK activity
GO:0005173 ISS stem cell factor receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0007275 IEA multicellular organismal development
GO:0009966 IEA regulation of signal transduction
GO:0010801 IMP negative regulation of peptidyl-threonine phosphorylation
GO:0016020 IEA membrane
GO:0019901 IPI protein kinase binding
GO:0030291 ISS protein serine/threonine kinase inhibitor activity
GO:0043517 ISS positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0090311 ISS regulation of protein deacetylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000093298 Spred2-201 protein_coding Mus_musculus 0 1375
ENSMUST00000093299 Spred2-001 protein_coding Mus_musculus 0 1079
ENSMUST00000121522 Gm14612-001 processed_pseudogene Mus_musculus 0 438
ENSMUST00000123036 Spred2-002 protein_coding Mus_musculus 0 396

Loading