C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polyribonucleotide nucleotidyltransferase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000447944 PNPT1-001 ENSG00000138035 9606 - 2:55634265-55693910 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000447944
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000447944 1.804±0.00 2.922±0.00 3.053±0.00 2.271±0.00 0.571±0.00 1.569±0.00 2.098±0.00 1.940±0.00 0.881±0.00 1.111±0.00 1.639±0.69 1.169±0.57 1.096±0.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000175 IDA:IEA 3'-5'-exoribonuclease activity
GO:0000957 IDA mitochondrial RNA catabolic process
GO:0000958 IDA mitochondrial mRNA catabolic process
GO:0000962 IDA positive regulation of mitochondrial RNA catabolic process
GO:0000964 IMP mitochondrial RNA 5'-end processing
GO:0000965 IMP mitochondrial RNA 3'-end processing
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0004654 IDA:IEA polyribonucleotide nucleotidyltransferase activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005758 IDA mitochondrial intermembrane space
GO:0006396 IEA RNA processing
GO:0006401 IDA RNA catabolic process
GO:0006402 IDA:IEA mRNA catabolic process
GO:0008266 IDA poly(U) RNA binding
GO:0016020 IEA membrane
GO:0034046 IDA poly(G) binding
GO:0034599 IDA cellular response to oxidative stress
GO:0035198 IDA miRNA binding
GO:0035458 IDA cellular response to interferon-beta
GO:0035927 IDA RNA import into mitochondrion
GO:0035928 IDA rRNA import into mitochondrion
GO:0043457 ISS regulation of cellular respiration
GO:0043631 IDA RNA polyadenylation
GO:0044822 IDA poly(A) RNA binding
GO:0045025 IDA mitochondrial degradosome
GO:0045926 IDA negative regulation of growth
GO:0051260 IDA protein homooligomerization
GO:0061014 IMP positive regulation of mRNA catabolic process
GO:0070207 IDA protein homotrimerization
GO:0070584 ISS mitochondrion morphogenesis
GO:0071042 IDA nuclear polyadenylation-dependent mRNA catabolic process
GO:0071850 IDA mitotic cell cycle arrest
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:0097222 IMP mitochondrial mRNA polyadenylation
GO:2000627 IDA positive regulation of miRNA catabolic process
GO:2000772 IDA regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020756 Pnpt1-001 protein_coding Mus_musculus 0 2708
ENSMUST00000154924 Pnpt1-002 processed_transcript Mus_musculus 0 1810
ENSMUST00000131527 Pnpt1-004 processed_transcript Mus_musculus 0 322
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.000006 58
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.000006 58

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