C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cathepsin B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000453527 CTSB-006 ENSG00000164733 9606 - 8:11844320-11868087 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000453527
Transcript ID Adipose Adrenal Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000453527 172.643±0.00 104.785±0.00 95.874±0.00 38.256±0.00 107.232±54.14 58.646±40.60 79.325±0.00 106.381±10.31 304.919±35.81 39.985±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Y4 CIL_0008Y4_0001 VISTA 8:11271783-11873892
CIL_000919 CIL_000919_0001 VISTA 8:11446673-12047186
CIL_0007PQ CIL_0007PQ_0001 VISTA 8:11649159-12249913

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002224 TAS toll-like receptor signaling pathway
GO:0004197 IEA:IDA cysteine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005518 IDA collagen binding
GO:0005576 TAS extracellular region
GO:0005615 ISS extracellular space
GO:0005622 TAS intracellular
GO:0005730 IDA nucleolus
GO:0005764 IDA lysosome
GO:0006508 IEA:IDA proteolysis
GO:0008233 IDA peptidase activity
GO:0008234 IEA:IDA cysteine-type peptidase activity
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030574 IDA collagen catabolic process
GO:0030855 IEP epithelial cell differentiation
GO:0036021 TAS endolysosome lumen
GO:0042981 TAS regulation of apoptotic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043394 IPI proteoglycan binding
GO:0045087 TAS innate immune response
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050790 IEA regulation of catalytic activity
GO:0051603 IDA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0097067 IEP cellular response to thyroid hormone stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000006235 Ctsb-201 protein_coding Mus_musculus 0 813

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