C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: membrane metallo-endopeptidase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000460393 MME-001 ENSG00000196549 9606 + 3:155079647-155183708 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastHeartKidneyLiverLungENST00000460393
Transcript ID Adipose Brain Breast Heart Kidney Liver Lung
ENST00000460393 7.005±0.00 0.011±0.00 8.508±7.42 0.097±0.00 13.043±0.00 0.523±0.00 5.616±0.88

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000669 CIL_000669_0001 CGP 3:154337672-155183729
CIL_000291 CIL_000291_0001 CGP 3:155024124-155745067

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IEP kidney development
GO:0002003 TAS angiotensin maturation
GO:0004175 IDA endopeptidase activity
GO:0004222 IEA:IMP metalloendopeptidase activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0005903 IDA brush border
GO:0005925 IDA focal adhesion
GO:0006508 IDA:IEA proteolysis
GO:0006518 ISS peptide metabolic process
GO:0008021 ISS synaptic vesicle
GO:0008233 IEA peptidase activity
GO:0008270 IDA zinc ion binding
GO:0016020 IEA membrane
GO:0016021 NAS integral component of membrane
GO:0019233 ISS sensory perception of pain
GO:0030424 ISS axon
GO:0030425 ISS dendrite
GO:0042277 ISS peptide binding
GO:0044267 TAS cellular protein metabolic process
GO:0044306 ISS neuron projection terminus
GO:0045202 ISS synapse
GO:0046449 IMP creatinine metabolic process
GO:0050435 ISS beta-amyloid metabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0071345 IDA cellular response to cytokine stimulus
GO:0071492 IDA cellular response to UV-A
GO:0071493 IDA cellular response to UV-B
GO:0090399 IEP replicative senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029400 Mme-201 protein_coding Mus_musculus 0 3066

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