C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dopamine receptor D3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000460779 DRD3-001 ENSG00000151577 9606 - 3:114128652-114199407 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalENST00000460779
Transcript ID Adrenal
ENST00000460779 0.037±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001591 ISS dopamine neurotransmitter receptor activity, coupled via Gi/Go
GO:0002031 IDA G-protein coupled receptor internalization
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006874 IDA cellular calcium ion homeostasis
GO:0007186 IDA:IEA G-protein coupled receptor signaling pathway
GO:0007191 IDA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007194 IDA negative regulation of adenylate cyclase activity
GO:0007195 IDA adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007611 NAS learning or memory
GO:0007612 NAS learning
GO:0007626 ISS locomotory behavior
GO:0008144 ISS drug binding
GO:0008542 ISS visual learning
GO:0014059 ISS regulation of dopamine secretion
GO:0016021 IEA integral component of membrane
GO:0030814 IDA regulation of cAMP metabolic process
GO:0032467 IMP positive regulation of cytokinesis
GO:0032922 ISS circadian regulation of gene expression
GO:0034776 IDA response to histamine
GO:0035176 NAS social behavior
GO:0042220 IEP response to cocaine
GO:0042417 IC dopamine metabolic process
GO:0042493 ISS response to drug
GO:0043278 ISS response to morphine
GO:0045776 ISS negative regulation of blood pressure
GO:0045840 ISS positive regulation of mitosis
GO:0046717 ISS acid secretion
GO:0048148 ISS behavioral response to cocaine
GO:0048715 ISS negative regulation of oligodendrocyte differentiation
GO:0050482 IDA arachidonic acid secretion
GO:0050709 IDA negative regulation of protein secretion
GO:0050883 ISS musculoskeletal movement, spinal reflex action
GO:0051584 IC regulation of dopamine uptake involved in synaptic transmission
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0060134 IMP prepulse inhibition
GO:0060161 ISS positive regulation of dopamine receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023390 Drd3-201 protein_coding Mus_musculus 0 872

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