C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000477593 PIK3CB-001 ENSG00000051382 9606 - 3:138654018-138834752 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000477593
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000477593 3.863±0.00 1.623±0.00 3.564±0.69 2.000±0.92 2.655±0.01 2.523±1.75 2.666±1.65 1.236±0.28 1.807±0.08 2.354±0.00 2.003±0.49 3.575±0.97 2.099±0.63

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0005886 IBA plasma membrane
GO:0005942 IBA phosphatidylinositol 3-kinase complex
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0006914 IEA autophagy
GO:0006935 TAS chemotaxis
GO:0007165 NAS signal transduction
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010508 TAS positive regulation of autophagy
GO:0014065 TAS phosphatidylinositol 3-kinase signaling
GO:0016303 IBA 1-phosphatidylinositol-3-kinase activity
GO:0016477 TAS cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0030168 TAS platelet activation
GO:0035004 TAS phosphatidylinositol 3-kinase activity
GO:0035005 IBA 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0046934 IBA phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 IEA:TAS phosphatidylinositol-mediated signaling
GO:0050852 TAS T cell receptor signaling pathway
GO:0050900 TAS leukocyte migration
GO:0070527 TAS platelet aggregation
GO:2000369 TAS regulation of clathrin-mediated endocytosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000035037 Pik3cb-001 protein_coding Mus_musculus 0 4614
ENSMUST00000136965 Pik3cb-002 nonsense_mediated_decay Mus_musculus 0 4588
ENSMUST00000121250 Gm12978-001 transcribed_processed_pseudogene Mus_musculus 0 603
ENSMUST00000124723 Pik3cb-003 protein_coding Mus_musculus 0 298

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