C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: roundabout, axon guidance receptor, homolog 1 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000495273 ROBO1-003 ENSG00000169855 9606 - 3:78598688-79019015 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverOvaryPlacentaTestisENST00000495273
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Ovary Placenta Testis
ENST00000495273 2.324±0.00 2.313±0.00 1.171±0.00 0.529±0.00 0.511±0.00 0.867±0.00 0.772±0.00 2.087±1.15 0.214±0.00 3.945±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002042 IMP cell migration involved in sprouting angiogenesis
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007155 TAS cell adhesion
GO:0007156 IDA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007399 TAS nervous system development
GO:0007411 TAS axon guidance
GO:0008046 TAS axon guidance receptor activity
GO:0009986 IDA cell surface
GO:0016199 ISS axon midline choice point recognition
GO:0021836 IDA chemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0030275 IPI LRR domain binding
GO:0033600 IMP negative regulation of mammary gland epithelial cell proliferation
GO:0035385 IMP Roundabout signaling pathway
GO:0042802 IDA identical protein binding
GO:0050772 IDA positive regulation of axonogenesis
GO:0050925 IDA negative regulation of negative chemotaxis
GO:0070100 IMP negative regulation of chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023600 Robo1-001 protein_coding Mus_musculus 0 3509

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