C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: metastasis suppressor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000518547 MTSS1-001 ENSG00000170873 9606 - 8:124550790-124728429 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000518547
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000518547 12.788±0.00 4.224±0.00 4.045±0.00 5.416±0.36 4.531±0.19 3.384±0.00 3.966±2.07 8.301±0.00 7.575±0.00 5.244±0.00 2.860±0.00 3.727±0.00 11.838±0.24 5.491±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004ZG CIL_0004ZG_0001 CGP 8:124488485-124568510
CIL_000461 CIL_000461_0001 CGP 8:124539103-124728429

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 NAS ruffle
GO:0003779 IEA actin binding
GO:0003785 IDA actin monomer binding
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005737 TAS cytoplasm
GO:0006928 NAS cellular component movement
GO:0007009 IEA plasma membrane organization
GO:0007155 NAS cell adhesion
GO:0007165 IEA signal transduction
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008093 IEA cytoskeletal adaptor activity
GO:0015629 IDA actin cytoskeleton
GO:0017124 IEA SH3 domain binding
GO:0030035 NAS microspike assembly
GO:0030036 TAS actin cytoskeleton organization
GO:0030139 TAS endocytic vesicle
GO:0042802 IPI identical protein binding
GO:0046847 IEA filopodium assembly
GO:0050680 ISS negative regulation of epithelial cell proliferation
GO:0061333 ISS renal tubule morphogenesis
GO:0071498 ISS cellular response to fluid shear stress
GO:0072102 ISS glomerulus morphogenesis
GO:0072160 ISS nephron tubule epithelial cell differentiation
GO:2001013 ISS epithelial cell proliferation involved in renal tubule morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000080371 Mtss1-201 protein_coding Mus_musculus 0 4883

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