C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: diacylglycerol O-acyltransferase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000528718 DGAT1-001 ENSG00000185000 9606 - 8:144314584-144326910 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverMuscleOvaryENST00000528718
Transcript ID Brain Breast Colon Heart Kidney Liver Muscle Ovary
ENST00000528718 4.030±0.00 8.211±7.17 1.072±0.00 0.572±0.00 5.896±0.00 2.212±1.22 2.940±0.00 10.321±1.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SS CIL_0007SS_0001 VISTA 8:143880613-144482307
CIL_00064A CIL_00064A_0002 CGP 8:144266560-144314722
CIL_00026U CIL_00026U_0001 CGP 8:144291591-144326910
CIL_00026R CIL_00026R_0001 CGP 8:144314584-144336281

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003846 IEA 2-acylglycerol O-acyltransferase activity
GO:0004144 IDA diacylglycerol O-acyltransferase activity
GO:0005515 IPI protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006641 TAS triglyceride metabolic process
GO:0006644 TAS phospholipid metabolic process
GO:0016020 IEA membrane
GO:0016021 ISS integral component of membrane
GO:0016310 IEA phosphorylation
GO:0016746 TAS transferase activity, transferring acyl groups
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019432 IDA triglyceride biosynthetic process
GO:0019915 ISS lipid storage
GO:0034379 IMP very-low-density lipoprotein particle assembly
GO:0035336 ISS long-chain fatty-acyl-CoA metabolic process
GO:0036155 TAS acylglycerol acyl-chain remodeling
GO:0042572 IEA retinol metabolic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046339 ISS diacylglycerol metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0050252 IEA retinol O-fatty-acyltransferase activity
GO:0055089 IEA fatty acid homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023214 Dgat1-001 protein_coding Mus_musculus 0 1325
ENSMUST00000159908 Dgat1-007 retained_intron Mus_musculus 0 444
ENSMUST00000160293 Dgat1-008 protein_coding Mus_musculus 0 422
ENSMUST00000160294 Dgat1-002 retained_intron Mus_musculus 0 396
ENSMUST00000162354 Dgat1-006 nonsense_mediated_decay Mus_musculus 0 257

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