C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cathepsin B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000533455 CTSB-002 ENSG00000164733 9606 - 8:11844355-11868106 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000533455
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000533455 287.071±0.00 93.900±0.00 51.260±0.00 78.812±46.53 137.392±85.01 90.628±62.07 88.004±77.72 145.275±60.79 120.300±110.66 171.736±147.88 85.804±70.27 104.495±66.65 177.686±30.84 37.625±28.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Y4 CIL_0008Y4_0001 VISTA 8:11271783-11873892
CIL_000919 CIL_000919_0001 VISTA 8:11446673-12047186
CIL_0007PQ CIL_0007PQ_0001 VISTA 8:11649159-12249913

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002224 TAS toll-like receptor signaling pathway
GO:0004197 IEA:IDA cysteine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005518 IDA collagen binding
GO:0005576 TAS extracellular region
GO:0005615 ISS extracellular space
GO:0005622 TAS intracellular
GO:0005730 IDA nucleolus
GO:0005764 IDA lysosome
GO:0006508 IEA:IDA proteolysis
GO:0008233 IDA peptidase activity
GO:0008234 IEA:IDA cysteine-type peptidase activity
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030574 IDA collagen catabolic process
GO:0030855 IEP epithelial cell differentiation
GO:0036021 TAS endolysosome lumen
GO:0042981 TAS regulation of apoptotic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043394 IPI proteoglycan binding
GO:0045087 TAS innate immune response
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050790 IEA regulation of catalytic activity
GO:0051603 IDA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0097067 IEP cellular response to thyroid hormone stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000006235 Ctsb-201 protein_coding Mus_musculus 0 813

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