C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: superoxide dismutase 2, mitochondrial
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000538183 SOD2-001 ENSG00000112096 9606 - 6:159669057-159693328 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastLiverLungTestisENST00000538183
Transcript ID Bladder Breast Liver Lung Testis
ENST00000538183 4.124±0.00 8.648±0.00 11.271±0.00 10.856±0.00 12.693±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089P CIL_00089P_0001 VISTA 6:159654795-160257694

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000302 IEA response to reactive oxygen species
GO:0000303 IMP response to superoxide
GO:0001306 IEA age-dependent response to oxidative stress
GO:0001315 IMP age-dependent response to reactive oxygen species
GO:0001666 IEA response to hypoxia
GO:0001836 ISS release of cytochrome c from mitochondria
GO:0001889 IEA liver development
GO:0003032 IEA detection of oxygen
GO:0003069 ISS vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
GO:0003677 IEA DNA binding
GO:0004784 IEA:IDA superoxide dismutase activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0006749 IEA glutathione metabolic process
GO:0006801 IDA:IEA superoxide metabolic process
GO:0006979 IEA response to oxidative stress
GO:0007005 IEA mitochondrion organization
GO:0007507 IEA heart development
GO:0007568 IEA aging
GO:0007626 IEA locomotory behavior
GO:0008217 ISS regulation of blood pressure
GO:0008285 IMP negative regulation of cell proliferation
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631 IEA intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0008637 IEA apoptotic mitochondrial changes
GO:0009314 IEA response to radiation
GO:0009409 IEA response to cold
GO:0009791 IEA post-embryonic development
GO:0010042 IEA response to manganese ion
GO:0010043 IEA response to zinc ion
GO:0010269 IEA response to selenium ion
GO:0010332 IEA response to gamma radiation
GO:0014823 IEA response to activity
GO:0019430 IMP removal of superoxide radicals
GO:0019825 IEA oxygen binding
GO:0022904 IEA respiratory electron transport chain
GO:0030097 IEA hemopoiesis
GO:0030145 TAS manganese ion binding
GO:0031667 IEA response to nutrient levels
GO:0032364 IMP oxygen homeostasis
GO:0032496 IEA response to lipopolysaccharide
GO:0033591 IEA response to L-ascorbic acid
GO:0034021 IEA response to silicon dioxide
GO:0035900 IEA response to isolation stress
GO:0035902 IEA response to immobilization stress
GO:0042311 IEA vasodilation
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0042554 IEA superoxide anion generation
GO:0042645 IEA mitochondrial nucleoid
GO:0042743 IEA hydrogen peroxide metabolic process
GO:0042802 IPI identical protein binding
GO:0043066 IEA negative regulation of apoptotic process
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0045429 IEA positive regulation of nitric oxide biosynthetic process
GO:0045599 IEA negative regulation of fat cell differentiation
GO:0046686 IEA response to cadmium ion
GO:0046872 IEA metal ion binding
GO:0048147 IEA negative regulation of fibroblast proliferation
GO:0048666 IEA neuron development
GO:0048678 IEA response to axon injury
GO:0048773 IEA erythrophore differentiation
GO:0050665 IEA hydrogen peroxide biosynthetic process
GO:0050790 IEA regulation of catalytic activity
GO:0051260 IEA protein homooligomerization
GO:0051289 IPI protein homotetramerization
GO:0051602 IEA response to electrical stimulus
GO:0051881 IEA regulation of mitochondrial membrane potential
GO:0055072 IEA iron ion homeostasis
GO:0055093 IEA response to hyperoxia
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0071000 IEA response to magnetism
GO:0071361 IEA cellular response to ethanol
GO:1902176 IMP negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000007012 Sod2-201 protein_coding Mus_musculus 0 767

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