C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: superoxide dismutase 2, mitochondrial
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000007012 Sod2-201 ENSMUSG00000006818 10090 + 17:13007839-13018119 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000007012
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000007012 11.763±3.09 143.463±98.50 22.459±6.56 21.455±8.93 37.275±38.14 45.016±22.71 79.249±16.24 56.645±26.97 19.360±7.46 8.183±0.57 42.393±2.34 62.754±31.08 9.158±5.50 16.436±11.70

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089P CIL_00089P_0002 VISTA 17:12489717-13093070
CIL_0003I5 CIL_0003I5_0002 CGP 17:12966796-13018119

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000302 IMP response to reactive oxygen species
GO:0000303 IMP response to superoxide
GO:0001306 IMP age-dependent response to oxidative stress
GO:0001315 ISS age-dependent response to reactive oxygen species
GO:0001666 IEA response to hypoxia
GO:0001836 IMP release of cytochrome c from mitochondria
GO:0001889 IMP liver development
GO:0003032 IMP detection of oxygen
GO:0003069 IMP vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
GO:0003677 IEA DNA binding
GO:0004784 ISS superoxide dismutase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0006357 ISS regulation of transcription from RNA polymerase II promoter
GO:0006749 IMP glutathione metabolic process
GO:0006801 ISS superoxide metabolic process
GO:0006979 IGI response to oxidative stress
GO:0007005 IMP mitochondrion organization
GO:0007507 IMP heart development
GO:0007568 IEA aging
GO:0007626 IMP locomotory behavior
GO:0008217 IMP regulation of blood pressure
GO:0008285 IEA negative regulation of cell proliferation
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631 IMP intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0008637 IMP apoptotic mitochondrial changes
GO:0009314 IEA response to radiation
GO:0009409 IEA response to cold
GO:0009791 IMP post-embryonic development
GO:0010042 IEA response to manganese ion
GO:0010043 IEA response to zinc ion
GO:0010269 IEA response to selenium ion
GO:0010332 IGI response to gamma radiation
GO:0014823 IMP response to activity
GO:0019430 IMP removal of superoxide radicals
GO:0019825 IEA oxygen binding
GO:0022904 IMP respiratory electron transport chain
GO:0030097 IMP hemopoiesis
GO:0030145 ISS manganese ion binding
GO:0031667 IEA response to nutrient levels
GO:0032364 IEA oxygen homeostasis
GO:0032496 IEA response to lipopolysaccharide
GO:0033591 IEA response to L-ascorbic acid
GO:0034021 IEA response to silicon dioxide
GO:0035900 IEA response to isolation stress
GO:0035902 IEA response to immobilization stress
GO:0042311 IMP vasodilation
GO:0042493 IEA response to drug
GO:0042542 IMP response to hydrogen peroxide
GO:0042554 IMP superoxide anion generation
GO:0042645 IEA mitochondrial nucleoid
GO:0042743 IEA hydrogen peroxide metabolic process
GO:0042802 IEA identical protein binding
GO:0043066 IEA negative regulation of apoptotic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045429 IMP positive regulation of nitric oxide biosynthetic process
GO:0045599 IMP negative regulation of fat cell differentiation
GO:0046686 IEA response to cadmium ion
GO:0048147 IDA negative regulation of fibroblast proliferation
GO:0048666 IMP neuron development
GO:0048678 IMP response to axon injury
GO:0048773 IMP erythrophore differentiation
GO:0050665 IEA hydrogen peroxide biosynthetic process
GO:0050790 IMP regulation of catalytic activity
GO:0051260 IEA protein homooligomerization
GO:0051289 IEA protein homotetramerization
GO:0051602 IEA response to electrical stimulus
GO:0051881 IMP regulation of mitochondrial membrane potential
GO:0055072 IMP iron ion homeostasis
GO:0055093 IMP response to hyperoxia
GO:0070062 IEA extracellular vesicular exosome
GO:0071000 IEA response to magnetism
GO:0071361 IEA cellular response to ethanol
GO:1902176 IEA negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000337404 SOD2-007 protein_coding Homo_sapiens 0 392
ENST00000367054 SOD2-016 protein_coding Homo_sapiens 0 392
ENST00000367055 SOD2-002 protein_coding Homo_sapiens 0 767
ENST00000401980 SOD2-011 protein_coding Homo_sapiens 0 228
ENST00000444946 SOD2-006 protein_coding Homo_sapiens 0 383
ENST00000452684 SOD2-003 protein_coding Homo_sapiens 0 228
ENST00000535459 SOD2-014 retained_intron Homo_sapiens 0 544
ENST00000535561 SOD2-008 protein_coding Homo_sapiens 0 510
ENST00000537657 SOD2-009 protein_coding Homo_sapiens 0 510
ENST00000538183 SOD2-001 protein_coding Homo_sapiens 0 767
ENST00000541573 SOD2-015 processed_transcript Homo_sapiens 0 544
ENST00000545162 SOD2-010 protein_coding Homo_sapiens 0 525
ENST00000546087 SOD2-004 protein_coding Homo_sapiens 0 767
ENST00000546260 SOD2-012 nonsense_mediated_decay Homo_sapiens 0 544

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