C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: presenilin 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000553855 PSEN1-024 ENSG00000080815 9606 + 14:73148020-73217158 nonsense_mediated_decay

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P0 CIL_0008P0_0001 VISTA 14:72878760-73482269
CIL_0003OW CIL_0003OW_0001 CGP 14:73058436-73223691
CIL_0001TQ CIL_0001TQ_0001 CGP 14:73136418-73274640

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000776 IDA kinetochore
GO:0004175 IDA endopeptidase activity
GO:0004190 IEA aspartic-type endopeptidase activity
GO:0005262 IMP calcium channel activity
GO:0005515 IPI protein binding
GO:0005640 IDA nuclear outer membrane
GO:0005739 IDA mitochondrion
GO:0005743 IBA mitochondrial inner membrane
GO:0005765 IBA lysosomal membrane
GO:0005783 IDA endoplasmic reticulum
GO:0005790 IDA smooth endoplasmic reticulum
GO:0005791 IDA rough endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005813 IDA centrosome
GO:0005887 IDA integral component of plasma membrane
GO:0005938 IBA cell cortex
GO:0006508 IEA proteolysis
GO:0006509 IDA membrane protein ectodomain proteolysis
GO:0007220 IBA Notch receptor processing
GO:0008013 IPI beta-catenin binding
GO:0009986 IBA cell surface
GO:0016020 IDA membrane
GO:0016021 IEA:TAS integral component of membrane
GO:0016324 IBA apical plasma membrane
GO:0016337 IMP single organismal cell-cell adhesion
GO:0016485 IDA protein processing
GO:0022617 TAS extracellular matrix disassembly
GO:0030018 IBA Z disc
GO:0030165 IPI PDZ domain binding
GO:0030198 TAS extracellular matrix organization
GO:0030424 IBA axon
GO:0030426 IBA growth cone
GO:0031594 IBA neuromuscular junction
GO:0031965 IDA nuclear membrane
GO:0032469 IGI endoplasmic reticulum calcium ion homeostasis
GO:0035253 IBA ciliary rootlet
GO:0035556 IEA intracellular signal transduction
GO:0042325 IDA regulation of phosphorylation
GO:0042987 IBA amyloid precursor protein catabolic process
GO:0043025 IBA neuronal cell body
GO:0043066 IDA negative regulation of apoptotic process
GO:0043085 IDA positive regulation of catalytic activity
GO:0043198 IBA dendritic shaft
GO:0045121 IBA membrane raft
GO:0045296 IBA cadherin binding
GO:0048471 IBA perinuclear region of cytoplasm
GO:0050435 IBA beta-amyloid metabolic process
GO:0051563 IBA smooth endoplasmic reticulum calcium ion homeostasis
GO:0060070 IBA canonical Wnt signaling pathway
GO:0070588 IMP calcium ion transmembrane transport
GO:0070765 IDA gamma-secretase complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000101225 Psen1-202 protein_coding Mus_musculus 0 1140
ENSMUST00000041806 Psen1-201 protein_coding Mus_musculus 0 1140

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