C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein tyrosine phosphatase, receptor type, C
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000573679 PTPRC-001 ENSG00000262418 9606 + CHR_HSCHR1_3_CTG31:198650527-198733963 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001915 ISS negative regulation of T cell mediated cytotoxicity
GO:0001960 ISS negative regulation of cytokine-mediated signaling pathway
GO:0002244 IMP hematopoietic progenitor cell differentiation
GO:0002378 IMP immunoglobulin biosynthetic process
GO:0004725 IDA:IEA protein tyrosine phosphatase activity
GO:0005001 TAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0005925 ISS focal adhesion
GO:0006469 ISS negative regulation of protein kinase activity
GO:0006470 ISS protein dephosphorylation
GO:0006933 IMP negative regulation of cell adhesion involved in substrate-bound cell migration
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007411 TAS axon guidance
GO:0009897 IDA external side of plasma membrane
GO:0016020 IDA membrane
GO:0016311 ISS dephosphorylation
GO:0019901 IPI protein kinase binding
GO:0030217 ISS T cell differentiation
GO:0030890 IMP positive regulation of B cell proliferation
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0042100 ISS B cell proliferation
GO:0042102 ISS positive regulation of T cell proliferation
GO:0044770 IMP cell cycle phase transition
GO:0045860 NAS positive regulation of protein kinase activity
GO:0048539 IMP bone marrow development
GO:0048864 IMP stem cell development
GO:0050852 IDA:IEA T cell receptor signaling pathway
GO:0050853 ISS B cell receptor signaling pathway
GO:0050857 ISS positive regulation of antigen receptor-mediated signaling pathway
GO:0051209 ISS release of sequestered calcium ion into cytosol
GO:0051607 ISS defense response to virus
GO:0051726 ISS regulation of cell cycle
GO:0070062 IDA extracellular vesicular exosome
GO:2000473 IMP positive regulation of hematopoietic stem cell migration
GO:2000648 IMP positive regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000183262 Ptprc-004 retained_intron Mus_musculus 0 254
ENSMUST00000182283 Ptprc-002 protein_coding Mus_musculus 0 211
ENSMUST00000182138 Ptprc-007 retained_intron Mus_musculus 0 206
ENSMUST00000182755 Ptprc-003 protein_coding Mus_musculus 0 206

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