C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein tyrosine phosphatase, receptor type, C
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000182283 Ptprc-002 ENSMUSG00000026395 10090 - 1:138063407-138175305 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000182283
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000182283 4.425±1.14 1.324±0.69 4.265±0.31 0.194±0.01 21.041±2.39 1.128±0.28 0.869±0.30 1.347±0.65 2.551±2.61 9.377±1.29 1.221±1.09 1.711±0.71 0.659±0.44 0.163±0.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IMP activation of MAPK activity
GO:0001916 IMP positive regulation of T cell mediated cytotoxicity
GO:0002711 IMP positive regulation of T cell mediated immunity
GO:0002923 IMP regulation of humoral immune response mediated by circulating immunoglobulin
GO:0002925 IMP positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0004725 IDA protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007159 IMP leukocyte cell-cell adhesion
GO:0008201 IDA heparin binding
GO:0009897 IDA external side of plasma membrane
GO:0030183 IMP B cell differentiation
GO:0030890 IMP positive regulation of B cell proliferation
GO:0031953 IMP negative regulation of protein autophosphorylation
GO:0034113 IMP heterotypic cell-cell adhesion
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0042098 IMP T cell proliferation
GO:0043395 IDA heparan sulfate proteoglycan binding
GO:0043410 IMP positive regulation of MAPK cascade
GO:0045059 IMP positive thymic T cell selection
GO:0045060 IMP negative thymic T cell selection
GO:0045577 IMP regulation of B cell differentiation
GO:0045582 IMP positive regulation of T cell differentiation
GO:0045588 IMP positive regulation of gamma-delta T cell differentiation
GO:0046641 IMP positive regulation of alpha-beta T cell proliferation
GO:0048304 IMP positive regulation of isotype switching to IgG isotypes
GO:0050732 IMP negative regulation of peptidyl-tyrosine phosphorylation
GO:0050852 IEA T cell receptor signaling pathway
GO:0050853 IMP B cell receptor signaling pathway
GO:0050855 IMP regulation of B cell receptor signaling pathway
GO:0051607 IDA defense response to virus
GO:0071944 IDA cell periphery
GO:2001236 IMP regulation of extrinsic apoptotic signaling pathway
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000105607 ptprc-201 protein_coding Danio_rerio 0 326
ENSDART00000137111 ptprc-001 protein_coding Danio_rerio 0 326
ENST00000348564 PTPRC-002 protein_coding Homo_sapiens 0 2143
ENST00000367367 PTPRC-005 protein_coding Homo_sapiens 0 784
ENST00000442510 PTPRC-001 protein_coding Homo_sapiens 0 2143
ENST00000529828 PTPRC-010 non_stop_decay Homo_sapiens 0 784
ENST00000530727 PTPRC-006 protein_coding Homo_sapiens 0 499
ENST00000573679 PTPRC-001 protein_coding Homo_sapiens 0 211
ENST00000575923 PTPRC-006 protein_coding Homo_sapiens 0 213

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