C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: aurora kinase B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000578549 AURKB-005 ENSG00000178999 9606 - 17:8204871-8210224 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartKidneyOvaryPlacentaENST00000578549
Transcript ID Heart Kidney Ovary Placenta
ENST00000578549 0.033±0.00 0.200±0.00 15.846±0.00 5.687±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0000779 IDA condensed chromosome, centromeric region
GO:0000780 IDA condensed nuclear chromosome, centromeric region
GO:0002903 IDA negative regulation of B cell apoptotic process
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004712 TAS protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005819 TAS spindle
GO:0005829 TAS cytosol
GO:0006468 IDA:IEA protein phosphorylation
GO:0008608 TAS attachment of spindle microtubules to kinetochore
GO:0009838 ISS abscission
GO:0016570 TAS histone modification
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030496 IDA midbody
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031565 ISS cytokinesis checkpoint
GO:0031577 IEA spindle checkpoint
GO:0032091 IDA negative regulation of protein binding
GO:0032133 IPI chromosome passenger complex
GO:0032466 ISS negative regulation of cytokinesis
GO:0032467 IMP positive regulation of cytokinesis
GO:0034501 IMP protein localization to kinetochore
GO:0034644 IDA cellular response to UV
GO:0035174 ISS histone serine kinase activity
GO:0036089 IDA cleavage furrow formation
GO:0043146 IMP spindle stabilization
GO:0043988 ISS histone H3-S28 phosphorylation
GO:0045171 IDA intercellular bridge
GO:0046777 TAS protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0051256 IMP spindle midzone assembly involved in mitosis
GO:0051983 TAS regulation of chromosome segregation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021277 Aurkb-001 protein_coding Mus_musculus 0 621
ENSMUST00000108666 Aurkb-002 protein_coding Mus_musculus 0 621
ENSMUST00000149018 Aurkb-005 retained_intron Mus_musculus 0 394
ENSMUST00000028997 Aurka-201 protein_coding Mus_musculus 0 206
ENSMUST00000109139 Aurka-002 protein_coding Mus_musculus 0 206
ENSMUST00000109140 Aurka-001 protein_coding Mus_musculus 0 206
ENSMUST00000128004 Aurka-004 retained_intron Mus_musculus 1.4013e-45 187

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