C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sprouty homolog 1, antagonist of FGF signaling (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000610581 SPRY1-201 ENSG00000164056 9606 + 4:123396795-123403760 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007AG CIL_0007AG_0001 CGP 4:122923074-123403760
CIL_0007V2 CIL_0007V2_0001 VISTA 4:123162273-123765299

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000132 IEA establishment of mitotic spindle orientation
GO:0001656 IEA metanephros development
GO:0001657 IEA ureteric bud development
GO:0001759 IEA organ induction
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008285 IEA negative regulation of cell proliferation
GO:0009966 IEA regulation of signal transduction
GO:0016020 IEA membrane
GO:0034261 IEA negative regulation of Ras GTPase activity
GO:0040037 IEA negative regulation of fibroblast growth factor receptor signaling pathway
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0043407 IEA negative regulation of MAP kinase activity
GO:0046580 IEA negative regulation of Ras protein signal transduction
GO:0051387 IEA negative regulation of neurotrophin TRK receptor signaling pathway
GO:0060449 IEA bud elongation involved in lung branching
GO:0070373 IEA negative regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000108107 Spry1-003 protein_coding Mus_musculus 0 870
ENSMUST00000038569 Spry1-001 protein_coding Mus_musculus 0 870
ENSMUST00000108109 Spry1-002 protein_coding Mus_musculus 0 870

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