C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proprotein convertase subtilisin/kexin type 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000611716 PCSK6-001 ENSG00000140479 9606 - 15:101303928-101489839 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonHeartKidneyLiverLungOvaryPlacentaENST00000611716
Transcript ID Brain Colon Heart Kidney Liver Lung Ovary Placenta
ENST00000611716 7.089±4.82 1.095±0.00 2.459±0.00 13.377±12.08 42.108±0.00 0.163±0.00 1.734±0.35 10.238±1.16

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004175 IDA endopeptidase activity
GO:0004252 IDA:IEA serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0005783 IEA endoplasmic reticulum
GO:0005796 TAS Golgi lumen
GO:0006508 IEA proteolysis
GO:0007354 IEA zygotic determination of anterior/posterior axis, embryo
GO:0007368 IEA determination of left/right symmetry
GO:0008201 IDA heparin binding
GO:0008233 IEA peptidase activity
GO:0009100 IDA glycoprotein metabolic process
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016485 IDA protein processing
GO:0016486 IDA peptide hormone processing
GO:0030510 TAS regulation of BMP signaling pathway
GO:0031012 IDA extracellular matrix
GO:0032455 TAS nerve growth factor processing
GO:0032902 IDA nerve growth factor production
GO:0032940 IDA secretion by cell
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048406 IDA nerve growth factor binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000055576 Pcsk6-001 protein_coding Mus_musculus 0 3655
ENSMUST00000098391 Pcsk6-002 protein_coding Mus_musculus 0 2122
ENSMUST00000176209 Pcsk6-003 protein_coding Mus_musculus 0 1954
ENSMUST00000177369 Pcsk6-005 retained_intron Mus_musculus 0 451

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